4-乙烯基-2,3-二氢苯并呋喃合成路线 （共 6 条）
反应条件
potassium tert-butylate in tetrahydrofuran T=0 - 20°C; 3.83333 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: EP1041980 B1, 2005 ;
Location in patent: Page/Page column 33 ;
反应条件
tetra(n-butyl)ammonium hydroxide; potassium iodide; sodium hydroxide in tert-butyl methyl ether; water T=50°C;
参考文献
WO2010/115897 A2, ;
Page/Page column 16-17 ;
反应条件
triethylamine; palladium diacetate; tris-(o-tolyl)phosphine T=20 - 80°C; P=9750.98 - 10501.1 Torr; AutoclaveInert atmosphere; Product distribution / selectivity;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP2236504 A1, 2010 ;
Location in patent: Page/Page column 6 ;
反应条件
tri-tert-butyl phosphine; cesium fluoride; tris(dibenzylideneacetone)dipalladium (0) in 1,4-dioxane Alkylation; 48 h; Heating;
参考文献
Zhu, Jingyang; Price, Benjamin A.; Zhao, Shannon X.; Skonezny, Paul M.
Tetrahedron Letters, 2000 , vol. 41, # 21 p. 4011 - 4014
反应条件
1.1: NaH / pyridine / 0.25 h / 40 °C 1.2: copper(I) chloride / pyridine / 2 h / Heating 2.1: 58 percent / t-Bu3P; CsF / Pd2(dba)3 / dioxane / 48 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 21 p. 4011 - 4014
反应条件
1: With 4-methylmorpholine N-oxide in dichloromethane T=-65°C; Jacobsen Asymmetric Epoxidation; Inert atmosphere; 2: With 3-chloro-benzenecarboperoxoic acid in ethanol; dichloromethane T=-65°C; Jacobsen Asymmetric Epoxidation; Inert atmosphere; SolventTemperatureReagent/catalystConcentration; enantioselective reaction;
参考文献
Siva Prasad; Vu, Truc; Totleben, Michael J.; Crispino, Gerard A.; Kacsur, David J.; Swaminathan, Shankar; Thornton, John E.; Fritz, Alan; Singh, Ambarish K.
Organic Process Research and Development, 2003 , vol. 7, # 6 p. 821 - 827
