1: methanol 2: NaBH4 / methanol 3: pyridine / benzene 4: various solvent(s) / 6 h / Heating 5: 25 percent / LiAlH4 / tetrahydrofuran / 1.) 3 h, room temp., 2.) 8 h, reflux View Scheme

1: pyridine / benzene 2: various solvent(s) / 6 h / Heating 3: 25 percent / LiAlH4 / tetrahydrofuran / 1.) 3 h, room temp., 2.) 8 h, reflux View Scheme

1: various solvent(s) / 6 h / Heating 2: 25 percent / LiAlH4 / tetrahydrofuran / 1.) 3 h, room temp., 2.) 8 h, reflux View Scheme

1: copper(l) iodide; caesium carbonate / acetonitrile / 24 h / 20 °C 2: toluene / 29 h / |Reflux View Scheme

1: palladium diacetate; dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; caesium carbonate / toluene / 26 h / 100 °C 2: palladium diacetate; potassium carbonate; 2,2,2-trimethylacetic acid / 24 h / 100 °C 3: boron tribromide / dichloromethane / 15.5 h / -78 - 20 °C 4: copper(l) iodide; caesium carbonate / acetonitrile / 24 h / 20 °C 5: toluene / 29 h / |Reflux View Scheme

1: iron; acetic acid / 4 h / 45 °C / |Inert atmosphere 2: caesium carbonate; palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl / toluene / 16 h / |Inert atmosphere; |Reflux 3: potassium carbonate; palladium diacetate; 2-oxo-3,3-dimethyl-butanoic acid / 23 h / 85 °C / |Inert atmosphere 4: palladium 10 on activated carbon; hydrogen / methanol; dichloromethane / 72 h / 20 °C / |Inert atmosphere 5: caesium carbonate; copper(l) chloride / acetonitrile / 35 h / 20 °C / |Inert atmosphere View Scheme

1: potassium carbonate / acetone / 2 h / |Inert atmosphere; |Reflux 2: iron; acetic acid / 4 h / 45 °C / |Inert atmosphere 3: caesium carbonate; palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl / toluene / 16 h / |Inert atmosphere; |Reflux 4: potassium carbonate; palladium diacetate; 2-oxo-3,3-dimethyl-butanoic acid / 23 h / 85 °C / |Inert atmosphere 5: palladium 10 on activated carbon; hydrogen / methanol; dichloromethane / 72 h / 20 °C / |Inert atmosphere 6: caesium carbonate; copper(l) chloride / acetonitrile / 35 h / 20 °C / |Inert atmosphere View Scheme

1: iron; acetic acid / 3.5 h / 45 °C / |Inert atmosphere 2: caesium carbonate; palladium diacetate; dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine / toluene / 26 h / 100 °C / |Inert atmosphere 3: potassium carbonate; palladium diacetate; 2-oxo-3,3-dimethyl-butanoic acid / toluene / 31.5 h / 100 °C / |Inert atmosphere 4: boron tribromide / dichloromethane / 15.5 h / -78 - 20 °C / |Inert atmosphere 5: caesium carbonate; copper(l) chloride / acetonitrile / 35 h / 20 °C / |Inert atmosphere View Scheme

1: caesium carbonate; palladium diacetate; dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine / toluene / 26 h / 100 °C / |Inert atmosphere 2: potassium carbonate; palladium diacetate; 2-oxo-3,3-dimethyl-butanoic acid / toluene / 31.5 h / 100 °C / |Inert atmosphere 3: boron tribromide / dichloromethane / 15.5 h / -78 - 20 °C / |Inert atmosphere 4: caesium carbonate; copper(l) chloride / acetonitrile / 35 h / 20 °C / |Inert atmosphere View Scheme

1: potassium carbonate; palladium diacetate; 2-oxo-3,3-dimethyl-butanoic acid / toluene / 31.5 h / 100 °C / |Inert atmosphere 2: boron tribromide / dichloromethane / 15.5 h / -78 - 20 °C / |Inert atmosphere 3: potassium carbonate; potassium iodide; copper(I) bromide / N,N-dimethyl-formamide / 20 h / 90 °C / |Inert atmosphere View Scheme