2,6-二甲基-4-噻吩-2-基-1,4-二氢吡啶-3,5-二羧酸二乙酯合成路线 （共 7 条）
反应条件
Mg3N2; ethanol; water T=80°C; Hantzsch pyridine synthesis;
参考文献
Bridgwood, Katy L.; Veitch, Gemma E.; Ley, Steven V.
Organic Letters, 2008 , vol. 10, # 16 p. 3627 - 3629
参考文献
Jiang, Ji-Long; Van Rhee, A. Michiel; Chang, Louis; Patchornik, Abraham; Ji, Xiao-Duo; Evans, Patricia; Melman, Neli; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 16 p. 2596 - 2608
反应条件
silica gel Hantzsch synthesis; 0.0333333 h; microwave irradiation;
参考文献
Yadav; Subba Reddy; Reddy
Synthetic Communications, 2001 , vol. 31, # 3 p. 425 - 430
反应条件
1: SOCl2 / CH2Cl2 / 1 h / 0 °C 2: CH2Cl2 / Ambient temperature View Scheme
参考文献
Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders
Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268
反应条件
in dichloromethane Ambient temperature; Yield given;
参考文献
Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders
Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268
参考文献
Grischkewitsch-Trochimowski; Mazurewitsch
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1912 , vol. 44, p. 575
Chem. Zentralbl., 1912 , vol. 83, # II p. 1561
反应条件
in chloroform 11 h; UV-irradiation; Product distribution; Further Variations:Solvents;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 14 p. 3423 - 3425
