1: With potassium hydroxide in ethanol; water 4 h; Reflux; 2: With hydrogenchloride in ethanol; water pH=1;

(6-(di-tert-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine)Ru(H)(CO); hydrogen in 1,4-dioxane T=115°C; P=7500.75 Torr; 38 h; Autoclave; chemoselective reaction;

1: sodium / anhydrous xylene / 5 h / |Inert atmosphere 2: trimethylsilyl iodide / dichloromethane / 21 h / 20 °C / |Inert atmosphere View Scheme

1: sodium / anhydrous xylene / 5 h / |Inert atmosphere 2: trimethylsilyl iodide / dichloromethane / 21 h / 20 °C / |Inert atmosphere 3: urea hydrogen peroxide addition compound; disodium hydrogenphosphate; trifluoroacetic anhydride / dichloromethane / 18 h / 20 °C / |Inert atmosphere; |Cooling with ice View Scheme