1: With sodium hydride in DMF (N,N-dimethyl-formamide)
T=0 - 100°C; 2.93333 h; Heating / reflux;
2: With hydrogenchloride in DMF (N,N-dimethyl-formamide); water
T=20°C;
参考文献
VICURON PHARMACEUTICALS, INC.
Patent: WO2004/7444 A2, 2004 ;
Location in patent: Page 99-100 ;
1: With sodium hydride in DMF (N,N-dimethyl-formamide)
T=0 - 20°C; 4.5 h; Heating / reflux;
2: With hydrogenchloride in DMF (N,N-dimethyl-formamide); water
T=20°C;
参考文献
VICURON PHARMACEUTICALS, INC.
Patent: WO2004/7444 A2, 2004 ;
Location in patent: Page 109 ;
