5-溴-1-苯并呋喃-2-甲醛合成路线 （共 6 条）
反应条件
sodium tetrahydroborate in ethanol; chloroform
参考文献
Mukhanova; Kukushkin; Ivanov; Alekseeva; Granik
Russian Chemical Bulletin, 2007 , vol. 56, # 2 p. 325 - 329
反应条件
1: 54 percent / 1) benzene, 90 min, reflux; 2) ethanol, 1 h
2: 97 percent / CH3ONa / methanol / 1 h
3: 36 percent / 2) 20 percent NaCN / 1) quinoline, 3 h, reflux; 2) ligroin, 3 h
View Scheme
参考文献
Dann, Otto; Char, Helmut; Griessmeier, Helmut
Liebigs Annalen der Chemie, 1982 , # 10 p. 1836 - 1869
反应条件
1: 54 percent / 1) benzene, 90 min, reflux; 2) ethanol, 1 h
2: 97 percent / CH3ONa / methanol / 1 h
3: 36 percent / 2) 20 percent NaCN / 1) quinoline, 3 h, reflux; 2) ligroin, 3 h
5: 2 N HCl / 1 h
View Scheme
参考文献
Dann, Otto; Char, Helmut; Griessmeier, Helmut
Liebigs Annalen der Chemie, 1982 , # 10 p. 1836 - 1869
反应条件
1: 70 percent
2: trimethylbenzyl ammonium hydroxide
3: hydrogen / Raney nickel / ethanol
View Scheme
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
反应条件
1: 70 percent
2: trimethylbenzyl ammonium hydroxide
3: hydrogen / Raney nickel / ethanol
4: 63 percent
View Scheme
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
