4-溴甲基-2-甲氧基-1-硝基苯合成路线 （共 6 条）
反应条件
carbon tetrabromide; triphenylphosphine in tetrahydrofuran T=20°C; 24 h; ConcentrationTime;
参考文献
CANCER RESEARCH TECHNOLOGY LIMITED; Bavetsias, Vassilios; Atrash, Butrus; Naud, Sébastien Gaston André; Sheldrake, Peter William; Blagg, Julian
Patent: US2013/345181 A1, 2013 ;
Location in patent: Paragraph 0713 ;
反应条件
triphenylphosphine in tetrahydrofuran T=20°C;
参考文献
CANCER RESEARCH TECHNOLOGY LIMITED; BAVETSIAS, Vassilios; ATRASH, Butrus; NAUD, Sebastien Gaston Andre; SHELDRAKE, Peter William; BLAGG, Julian
Patent: WO2012/123745 A1, 2012 ;
Location in patent: Page/Page column 87 ;
WO 2012/123745 A1
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 72 h; Heating;
参考文献
Ismail, Ibrahim A.; Sharp, Dale E.; Chedekel, Miles R.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2243 - 2246
反应条件
1: 90 percent / aq. NaOH / H2O / 80 °C 2: 73 percent / NBS, dibenzoyl peroxide / CCl4 / 72 h / Heating View Scheme
参考文献
Ismail, Ibrahim A.; Sharp, Dale E.; Chedekel, Miles R.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2243 - 2246
反应条件
triethylamine in tetrahydrofuran; dichloromethane
参考文献
Keegan, Kathleen S.; Kesicki, Edward A.; Gaudino, John Joseph; Cook, Adam Wade; Cowen, Scott Douglas; Burgess, Laurence Edward
Patent: US2003/69284 A1, 2003 ;
US 20030069284 A1
反应条件
(i) hexamethylenetetramine, (ii) aq. AcOH; Multistep reaction;
参考文献
Julia,M.; Chastrette,F.
Bulletin de la Societe Chimique de France, 1962 , p. 2255 - 2261
