N,N-二乙基-2-氯乙酰胺合成路线 （共 70 条）
参考文献
Sou
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1930 , vol. 191, p. 944,945
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1931 , vol. 192, p. 1462 - 1464
反应条件
1: 58 percent / NaH / tetrahydrofuran / 2 h / 20 °C 2: 77 percent / KOH / ethanol / 12 h / 0 °C 3: 50 percent / 0.25 h / 150 °C / 4 Torr 4: 76 percent / LiAlH4 / diethyl ether / 1 h / 0 - 20 °C View Scheme
参考文献
Seguin, Helene; Gardette, Daniel; Moreau, Marie-France; Madelmont, Jean-Claude; Gramain, Jean-Claude
Synthetic Communications, 1998 , vol. 28, # 22 p. 4257 - 4272
反应条件
nickel in tetrahydrofuran T=20°C; 2 h;
参考文献
Barrero; Alvarez-Manzaneda; Chahboun; Meneses; Romera
Synlett, 2001 , # 4 p. 485 - 488
参考文献
Am.Home Prod.Corp.
Patent: US2676188 , 1950 ;
反应条件
monobromoacetic acid chloride in dichloromethane
参考文献
Speziale,A.J.; Smith,L.R.
Journal of Organic Chemistry, 1962 , vol. 27, p. 4361 - 4365
反应条件
T=165 - 170°C; P=160 - 200 Torr;
参考文献
Chauzov, V. A.; Studnev, Yu. N.; Iznoskova, M. G.; Fokin, A. V.
J. Gen. Chem. USSR (Engl. Transl.), 1987 , vol. 57, # 1 p. 110 - 113,93 - 95
反应条件
in benzene Ambient temperature;
参考文献
Fernandez,M.V.; Durante-Lanes,P.
Tetrahedron, 1990 , vol. 46, p. 7911
反应条件
potassium carbonate in acetone
参考文献
Jenkins, Thomas E.; Axt, Sabine; Bolton, Jennifer
Patent: US2003/153554 A1, 2003 ;
反应条件
potassium carbonate in acetonitrile T=20°C; 5 h; Further byproducts given;
参考文献
Aladzheva, I. M.; Odinets, I. L.; Petrovskii, P. V.; Mastryukova, T. A.; Kabachnik, M. I.
Russian Journal of General Chemistry, 1993 , vol. 63, # 3.2 p. 431 - 437
Zhurnal Obshchei Khimii, 1993 , vol. 63, # 3 p. 611 - 620
反应条件
potassium carbonate in acetonitrile T=20°C; 5 h; Further byproducts given;
参考文献
Aladzheva, I. M.; Odinets, I. L.; Petrovskii, P. V.; Mastryukova, T. A.; Kabachnik, M. I.
Russian Journal of General Chemistry, 1993 , vol. 63, # 3.2 p. 431 - 437
Zhurnal Obshchei Khimii, 1993 , vol. 63, # 3 p. 611 - 620
