(1R,2S)-(-)-2-氨基-1,2-二苯基乙醇合成路线 （共 45 条）
反应条件
reagiert als Hydrochlorid;
参考文献
Read; Campbell
Journal of the Chemical Society, 1930 , p. 2377
Nature (London, United Kingdom), 1930 , vol. 125, p. 16
Full Text Show Details
Read; Steele
Journal of the Chemical Society, 1927 , p. 916 Anm.
反应条件
reagiert als Hydrochlorid;
参考文献
Read; Campbell
Journal of the Chemical Society, 1930 , p. 2377
Nature (London, United Kingdom), 1930 , vol. 125, p. 16
Full Text Show Details
Read; Steele
Journal of the Chemical Society, 1927 , p. 916 Anm.
反应条件
1: 1) HCl(g) / 1) Acetic acid, 80 degC, 9 h, 2) acetic acid, r.t., 5 h 2: 37.3 percent / KMnO4, CaSO4*2H2O / H2O; 2-methyl-propan-2-ol / 2 h / 60 °C 3: 75 percent / conc. H2SO4 / methanol / 2 h / Heating View Scheme
参考文献
Harada; Shiono
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 4 p. 1040 - 1045
反应条件
reagiert als Hydrochlorid;
参考文献
Read; Campbell
Journal of the Chemical Society, 1930 , p. 2377
Nature (London, United Kingdom), 1930 , vol. 125, p. 16
Full Text Show Details
Read; Steele
Journal of the Chemical Society, 1927 , p. 916 Anm.
反应条件
potassium carbonate in acetonitrile T=60°C; Substitution; 16 h;
参考文献
Petra, Danielle G. I.; Kamer, Paul C. J.; Van Leeuwen, Piet W. N. M.; Goubitz, Kees; Van Loon, Arjen M.; De Vries, Johannes G.; Schoemaker, Hans E.
European Journal of Inorganic Chemistry, 1999 , # 12 p. 2335 - 2341
反应条件
1: ethanol / 3 h / 20 °C 2: 2.7 g / sodium borohydride / ethanol / 1 h / 20 °C View Scheme
参考文献
Chen, Guoshu; Li, Xin; Zhang, Haile; Gong, Liuzhu; Mi, Aiqiao; Cui, Xin; Jiang, Yaozhong; Choi, Michael C.K.; Chan, Albert S.C.
Tetrahedron Asymmetry, 2002 , vol. 13, # 8 p. 809 - 813
反应条件
triethylamine in tetrahydrofuran T=20°C; 18 h;
参考文献
Chemical Communications, , vol. 49, # 80 p. 9131 - 9133
反应条件
1: methanol / |Resolution of racemate 2: ammonium hydroxide / water / 60 °C View Scheme
参考文献
Shitara, Hiroaki; Shintani, Toshiki; Kodama, Koichi; Hirose, Takuji
Journal of Organic Chemistry, 2013 , vol. 78, # 18 p. 9309 - 9316
反应条件
1: Et3N / tetrahydrofuran / 1 h / 20 °C 2: aq. NaHCO3 / CH2Cl2 / 1 h / 0 °C 3: p-TsOH*H2O / toluene View Scheme
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine 1.) THF, 2.) CH2Cl2, 3.) benzene, reflux; Yield given. Multistep reaction;
参考文献
Schuerman, Marla A.; Keverline, Kathryn I.; Hiskey, Richard G.
Tetrahedron Letters, 1995 , vol. 36, # 6 p. 825 - 828
