(1R,2S)-(-)-2-氨基-1,2-二苯基乙醇合成路线 （共 45 条）
反应条件
1: Et3N / tetrahydrofuran / 1 h / 20 °C 2: toluene / 10 h / Heating 3: p-TsOH*H2O / toluene View Scheme
参考文献
Yeo, David J.; Warriner, Stuart L.; Wilson, Andrew J.
Chemical Communications, 2013 , vol. 49, # 80 p. 9131 - 9133
反应条件
1: With dichlorobis(dicyclohexylphosphinomethylpyridine)–ruthenium (II); potassium tert-butylate T=165°C; 24 h; Inert atmosphere; 2: With sodium tetrahydroborate in methanol T=20°C; Inert atmosphere;
参考文献
Iida, Kazuki; Miura, Takashi; Ando, Junki; Saito, Susumu
Organic Letters, 2013 , vol. 15, # 7 p. 1436 - 1439
反应条件
1: Et3N / tetrahydrofuran / 1 h / 20 °C 2: toluene / 10 h / Heating View Scheme
参考文献
Synlett, , # 4 art. no. Y04304ST, p. 693 - 696
反应条件
1: 84.3 percent / triethylamine / tetrahydrofuran / 18 h 2: NaHCO3, NaCl / CHCl3; H2O / 20 h / Heating 3: 73.4 percent / p-toluenesulfonic acid monohydrate, CaCl2 / benzene / 8 h / Heating 4: N-bromosuccinimide / CCl4 / 1 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, # 5 p. 1547 - 1557
反应条件
1: With dichlorobis(dicyclohexylphosphinomethylpyridine)–ruthenium (II); potassium tert-butylate
T=165°C; 24 h; Inert atmosphere;
2: With sodium tetrahydroborate in methanol
T=20°C; Inert atmosphere;
参考文献
Iida, Kazuki; Miura, Takashi; Ando, Junki; Saito, Susumu
Organic Letters, 2013 , vol. 15, # 7 p. 1436 - 1439
