3-氨基-5-硝基苯甲酸甲酯合成路线 （共 12 条）
反应条件
acetyl chloride T=80°C; 48 h;
参考文献
Mancuso, Lena; Juerjens, Gerrit; Hermane, Jekaterina; Harmrolfs, Kirsten; Eichner, Simone; Fohrer, Joerg; Collisi, Wera; Sasse, Florenz; Kirschning, Andreas
Organic Letters, 2013 , vol. 15, # 17 p. 4442 - 4445
反应条件
formic acid; triethylamine; palladium on activated charcoal T=100°C; 1 h;
参考文献
Terpko, Marc O.; Heck, Richard F.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4992 - 4993
反应条件
2: 65 percent / triethylamine, 97percent formic acid / 10percent Pd on C / 1 h / 100 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 45, # 24 p. 4992 - 4993
反应条件
1: HCl 2: hydrogen sulfide; concentrated ammonia; alcohol View Scheme
参考文献
Chemische Berichte, , vol. 28, p. 597
反应条件
methanol; ammonia Einleiten von Schwefelwasserstoff;
参考文献
Journal of the Chemical Society, , vol. 87, p. 1265
反应条件
in dichloromethane T=25°C; KineticsMechanism;
参考文献
Lapshin, S. A.; Dadali, V. A.; Litvinenko, L. M.; Simanenko, Yu. S.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, p. 1730 - 1735
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, p. 1938 - 1944
反应条件
durch Austausch von NH2 gegen Chlor nach der Sandmeyerschen Methode;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/144127 A1, 2007 ;
Location in patent: Page/Page column 37 ;
WO 2007/144127 A1
反应条件
hydrogenchloride; water; copper (I) cyanide Diazotization.weiteres Reagens: Benzol; anschliessendes Erwaermen;
参考文献
Barber; Slack
Journal of the Chemical Society, 1947 , p. 82
反应条件
1: aqueous hydrochloric acid; copper (I)-cyanide; water / Diazotization.weiteres Reagens: Benzol; anschliessendes Erwaermen 2: ethanolic ammonia 3: phosphorus (V)-oxide; xylene View Scheme
参考文献
Barber; Slack
Journal of the Chemical Society, 1947 , p. 82
反应条件
TPGS–750–M; ammonium chloride; zinc in water T=20°C; 4 h; Green chemistry; ConcentrationReagent/catalystTime; chemoselective reaction;
参考文献
Kelly, Sean M.; Lipshutz, Bruce H.
Organic Letters, 2014 , vol. 16, # 1 p. 98 - 101
