1-苄基-1H-咪唑-2-硫醇合成路线 （共 14 条）
反应条件
1: With sodium tetrahydroborate; lithium chloride in ethylene glycol dimethyl ether; ethanol T=-15 - -5°C; 6 h; 2: With hydrogenchloride in ethylene glycol dimethyl ether; ethanol 0.5 h; Further stages.;
参考文献
Wolfe, Derek M.; Schreiner, Peter R.
Synthesis, 2007 , # 13 p. 2002 - 2008
反应条件
1: sodium borohydride / ethanol / 24 h / Ambient temperature 2: 12 N HCl / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Kruse; Kaiser; DeWolf Jr.; Frazee; Garvey; Hilbert; Faulkner; Flaim; Sawyer; Berkowitz
Journal of Medicinal Chemistry, 1986 , vol. 29, # 12 p. 2465 - 2472
反应条件
1: 0.33 h / Heating 2: sodium borohydride / ethanol / 24 h / Ambient temperature 3: 12 N HCl / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Kruse; Kaiser; DeWolf Jr.; Frazee; Garvey; Hilbert; Faulkner; Flaim; Sawyer; Berkowitz
Journal of Medicinal Chemistry, 1986 , vol. 29, # 12 p. 2465 - 2472
反应条件
1.1: aq. KOH / ethanol / 3 h 2.1: 8.86 g / aq. H2SO4 / acetone 3.1: NaBH4; LiCl / 1,2-dimethoxy-ethane; ethanol / 6 h / -15 - -5 °C 3.2: 88 percent / conc. HCl / 1,2-dimethoxy-ethane; ethanol / 0.5 h View Scheme
参考文献
Yamada; Yura; Morimoto; Harada; Honma; Kinoshita; Sugiura
Journal of Medicinal Chemistry, 1996 , vol. 39, # 2 p. 596 - 604
反应条件
hydrogenchloride in ethanol; water 2 h; Heating; Yield given;
参考文献
Kruse; Kaiser; DeWolf Jr.; Frazee; Garvey; Hilbert; Faulkner; Flaim; Sawyer; Berkowitz
Journal of Medicinal Chemistry, 1986 , vol. 29, # 12 p. 2465 - 2472
参考文献
Jones et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 4000
反应条件
hydrogenchloride; ethanol
参考文献
Jones
Journal of the American Chemical Society, 1949 , vol. 71, p. 383,384
Full Text Show Details
Jones et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 4000
反应条件
hydrogenchloride; ethanol
参考文献
Jones
Journal of the American Chemical Society, 1949 , vol. 71, p. 383,384
Full Text Show Details
Jones et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 4000
反应条件
1: toluene / 18 h / Heating 2: AcOH, HCl / 18 h / Heating View Scheme
参考文献
Yamada; Yura; Morimoto; Harada; Honma; Kinoshita; Sugiura
Journal of Medicinal Chemistry, 1996 , vol. 39, # 2 p. 596 - 604
反应条件
hydrogenchloride; acetic acid 18 h; Heating;
参考文献
Matsuda, Koyo; Yanagisawa, Isao; Isomura, Yasuo; Mase, Toshiyasu; Shibanuma, Tadao
Synthetic Communications, 1997 , vol. 27, # 20 p. 3565 - 3571
