1,3-二甲基-2-(4-氯苯基)咪唑烷合成路线 （共 7 条）
反应条件
toluene-4-sulfonic acid in toluene Heating;
参考文献
Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Siotto, Immacolata
Tetrahedron, 2005 , vol. 61, # 13 p. 3177 - 3182
反应条件
1: With naphthalene; lithium in tetrahydrofuran T=-40°C; 3 h; 2: With water in tetrahydrofuran T=-40°C; 0.5 h;
参考文献
Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Siotto, Immacolata
Tetrahedron, 2005 , vol. 61, # 13 p. 3177 - 3182
反应条件
1: 1,3-dimethyl-2-(4-chlorophenyl)imidazolidine With naphthalene; lithium in tetrahydrofuran T=-40°C; 3 h; 2: methyl chloroformate in tetrahydrofuran T=-80°C; 0.5 h; 3: With sulfuric acid in tetrahydrofuran; water T=20°C; 1 h;
参考文献
Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Siotto, Immacolata
Tetrahedron, 2005 , vol. 61, # 13 p. 3177 - 3182
反应条件
1.1: Li; naphthalene / tetrahydrofuran / 3 h / -40 °C 1.2: tetrahydrofuran / 0.5 h / -80 °C 2.1: H2SO4 / H2O; tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Siotto, Immacolata
Tetrahedron, 2005 , vol. 61, # 13 p. 3177 - 3182
反应条件
1.1: Li; naphthalene / tetrahydrofuran / 3 h / -40 °C 1.2: H2O / tetrahydrofuran / 0.5 h / -40 °C 2.1: Li; naphthalene / tetrahydrofuran / 8 h / -20 °C 2.2: 85 percent / H2O / tetrahydrofuran / 0.5 h View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Siotto, Immacolata
Tetrahedron, 2005 , vol. 61, # 13 p. 3177 - 3182
反应条件
1.1: Li; naphthalene / tetrahydrofuran / 3 h / -40 °C
1.2: tetrahydrofuran / 0.5 h / -40 °C
2.1: H2SO4 / H2O; tetrahydrofuran / 1 h / 20 °C
View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Siotto, Immacolata
Tetrahedron, 2005 , vol. 61, # 13 p. 3177 - 3182
反应条件
1.1: Li; naphthalene / tetrahydrofuran / 3 h / -40 °C
1.2: tetrahydrofuran / 0.5 h / -40 °C
2.1: H2SO4 / H2O; tetrahydrofuran / 1 h / 20 °C
View Scheme
参考文献
Azzena, Ugo; Dettori, Giovanna; Pisano, Luisa; Siotto, Immacolata
Tetrahedron, 2005 , vol. 61, # 13 p. 3177 - 3182
