1-(3-硝基苯基)-1H-咪唑合成路线 （共 10 条）
反应条件
caesium carbonate; copper(I) bromide in dimethyl sulfoxide T=80°C; Ullmann coupling; 24 h;
参考文献
Yang, Minghua; Liu, Fei
Journal of Organic Chemistry, 2007 , vol. 72, # 23 p. 8969 - 8971
反应条件
polystrene supported copper furfural catalyst in methanol T=40°C; 12 h; Inert atmosphere;
参考文献
Islam, Sk.Manirul; Salam, Noor; Mondal, Paramita; Roy, Anupam Singha; Ghosh, Kajari; Tuhina
Journal of Molecular Catalysis A: Chemical, 2014 , vol. 387, p. 7 - 19
反应条件
copper(l) iodide; potassium carbonate; L-proline in dimethyl sulfoxide T=85°C; 40 h;
参考文献
Zhang, Hui; Cai, Qian; Ma, Dawei
Journal of Organic Chemistry, 2005 , vol. 70, # 13 p. 5164 - 5173
反应条件
1: 1H-imidazole With sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 1 h; 2: 1-fluoro-3-nitro benzene in N,N-dimethyl-formamide T=100°C;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2007/4749 A1, 2007 ;
Location in patent: Page/Page column 120 ;
WO 2007/004749 A1
反应条件
potassium carbonate; copper(II) oxide in N,N-dimethyl-formamide T=120°C; 17 h;
参考文献
Kantam, M. Lakshmi; Yadav, Jagjit; Laha, Soumi; Sreedhar, Bojja; Jha, Shailendra
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 11-12 p. 1938 - 1942
反应条件
potassium carbonate in dimethyl sulfoxide T=105 - 110°C; 25.5 h;
参考文献
Paul, Rolf; Hallett, William A.; Hanifin, John W.; Reich, Marvin F.; Johnson, Bernard D.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 19 p. 2716 - 2725
反应条件
potassium carbonate in water
参考文献
Neurosearch A/S; Meiji Seika Kaisha, Ltd.
Patent: US5902813 A1, 1999 ;
反应条件
Bu4(1+)*I(1-); anhydrous cobalt diacetate; potassium carbonate in N,N-dimethyl-formamide T=80°C; Arylation; 8 h;
参考文献
Wang; Chen
Journal of Chemical Research - Part S, 2000 , # 8 p. 367 - 369
反应条件
hydrogen; palladium 10 on activated carbon in acetic acid P=2585.81 Torr; 3 h;
参考文献
EP1214319 B1, ;
Page/Page column 14 ;
反应条件
potassium carbonate; dimethyl sulfoxide in ethanol; water; ethyl acetate
