1-氰基-2,3,5-三苯甲酰氧基-β-D-呋喃核糖合成路线 （共 26 条）
反应条件
4-(N,N-dimethlyamino)pyridine in ethanol; dichloromethane
参考文献
The United States of America as represented by the Department of Health and Human Services
Patent: US4451648 A1, 1984 ;
反应条件
4-(N,N-dimethlyamino)pyridine; hydrogen sulfide in ethanol
Addition; 18 h;
参考文献
Ramasamy, Kanda S.; Averett, Devron
Nucleosides and Nucleotides, 1999 , vol. 18, # 11-12 p. 2425 - 2431
反应条件
in ethanol; water; dimethyl sulfoxide; ethyl acetate
参考文献
ICN Pharmaceuticals, Inc.
Patent: US5907036 A1, 1999 ;
反应条件
1: 71 percent / triethylamine / methanol / 2 h / 20 °C
2: 74 percent / bromotrichloromethane; 1,8-diazabicyclo[5.4.0]-undec-7-ene / CH2Cl2 / 16 h / 0 °C
View Scheme
参考文献
Ramasamy, Kanda S.; Averett, Devron
Nucleosides and Nucleotides, 1999 , vol. 18, # 11-12 p. 2425 - 2431
反应条件
1: Et3N / methanol / 3 h / 20 °C
2: 85 percent / MnO2 / benzene / 12 h / Heating
View Scheme
参考文献
Ramasamy, Kanda S.; Bandaru, Rajanikanth; Averett, Devron
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5849 - 5851
反应条件
1: 70 percent / methanol / 2.5 h / Ambient temperature
2: 71.3 percent / dimethylsulfoxide / 20 h / Ambient temperature
3: 62.2 percent / 0.25 h / 135 °C / 0.1 Torr
View Scheme
参考文献
Poonian; Nowoswiat
Journal of Organic Chemistry, 1980 , vol. 45, # 2 p. 203 - 208
