(R)-(-)-1,2,3,4-四氢-1-萘酚合成路线 （共 59 条）
反应条件
potassium carbonate in methanol
参考文献
Merlic; Walsh
Journal of Organic Chemistry, 2001 , vol. 66, # 7 p. 2265 - 2274
反应条件
magnesium sulfate in tetrahydrofuran; dichloromethane
反应条件
Pseudomonas monteilii TA-5 cells T=30°C; pH=7.0; 7 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Lie, Felicia; Chen, Yongzheng; Wang, Zunsheng; Li, Zhi
Tetrahedron Asymmetry, 2009 , vol. 20, # 10 p. 1206 - 1211
反应条件
Rhodotorula glutinis 16740 in various solvent(s) pH=5.5 - 6.0;
参考文献
Homann, Michael J.; Vail, Robert B.; Previte, Edward; Tamarez, Maria; Morgan, Brian; Dodds, David R.; Zaks, Aleksey
Tetrahedron, 2004 , vol. 60, # 3 p. 789 - 797
反应条件
iodosylbenzene; (salen)manganese(III) complex (C104H90MnN2O2Si2(1+)*PF6(1-)) in chlorobenzene T=-20°C; 20 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 54, # 34 p. 10017 - 10028
反应条件
pseudomonas monteilii TA-5 monooxygenase; tris(hydroxymethyl)methylamine hydrochloride in methanol T=30°C; pH=7; 0.25 h; aq. bufferEnzymatic reaction;
参考文献
Chemical Communications, , vol. 47, # 11 p. 3284 - 3286
反应条件
1: 1-hydroxy-1,2,3,4-tetrahydronaphthalene With (-)-Tetramisole; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=-78°C; Inert atmosphereMolecular sieveResolution of racemate; 2: triphenyl-silyl chloride in tetrahydrofuran T=-78°C; 24 h; Inert atmosphereMolecular sieveResolution of racemate; enantioselective reaction;
参考文献
Akhani, Ravish K.; Moore, Maggie I.; Pribyl, Julia G.; Wiskur, Sheryl L.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2384 - 2396
反应条件
[(C4Ph4COHOCC4Ph4)(μ-H)][(CO)4Ru2]; Novozym(R) 435; 2,4-dimethylpentan-3-one in toluene T=70°C; P=142.511 Torr; 68 h;
参考文献
Verzijl, Gerard K.M.; De Vries, Johannes G.; Broxterman, Quirinus B.
Tetrahedron Asymmetry, 2005 , vol. 16, # 9 p. 1603 - 1610
反应条件
1: 1-hydroxy-1,2,3,4-tetrahydronaphthalene With (-)-Tetramisole; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=-78°C; Inert atmosphereMolecular sieveResolution of racemate; 2: chlorotris(p-methylphenyl)silane in tetrahydrofuran T=-78°C; 48 h; Inert atmosphereMolecular sieveResolution of racemate; enantioselective reaction;
参考文献
Akhani, Ravish K.; Moore, Maggie I.; Pribyl, Julia G.; Wiskur, Sheryl L.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2384 - 2396
反应条件
1: cis-4-hydroxy-3,4-dihydro-1-benzopyran With (-)-Tetramisole; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=-78°C; Inert atmosphereMolecular sieveResolution of racemate; 2: chlorotris(4-ethylphenyl)silane in tetrahydrofuran T=-78°C; 48 h; Inert atmosphereMolecular sieveResolution of racemate; enantioselective reaction;
参考文献
Akhani, Ravish K.; Moore, Maggie I.; Pribyl, Julia G.; Wiskur, Sheryl L.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2384 - 2396
