(S)-(+)-1,2,3,4-四氢-1-萘胺合成路线 （共 22 条）
反应条件
1: 4 Angstroem molecular sieves / benzene / 24 h / Ambient temperature 2: 1.) H2, PtO2, 2.) NaIO4 / 1.) C6H6, 2.) CH3OH, RT, 5 h View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 4, # 9 p. 2095 - 2100
反应条件
hydrogenchloride in methanol T=25°C; 3 h;
参考文献
Sugi, Kiyoaki D.; Nagata, Takushi; Yamada, Tohru; Mukaiyama, Teruaki
Chemistry Letters, 1997 , # 6 p. 493 - 494
Title/Abstract Full Text View citing articles Show Details
Yamada, Tohru; Nagata, Takushi; Sugi, Kiyoaki D.; Yorozu, Kiyotaka; Ikeno, Taketo; Ohtsuka, Yuhki; Miyazaki, Daichi; Mukaiyama, Teruaki
Chemistry - A European Journal, 2003 , vol. 9, # 18 p. 4485 - 4509
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction; enantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 100, p. 32 - 39
反应条件
Novozym 435 T=23°C; 2 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 23, # 3-4 p. 230 - 236
反应条件
hydrogenchloride; (+)-ketopinic acid; water; lithium diisopropyl amide Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron: Asymmetry, , vol. 5, # 5 p. 817 - 820
反应条件
1: With (Ph)2SiH2; silver trifluoromethanesulfonate in ethylene glycol dimethyl ether T=20°C; 25 h; 2: With hydrogenchloride in methanol; ethylene glycol dimethyl ether Further stages. Title compound not separated from byproducts.;
参考文献
Chemical Communications, , # 22 p. 2360 - 2361
反应条件
Candida antarctica lipase B in n-heptane T=80°C; 26 h;
参考文献
Journal of Organic Chemistry, , vol. 72, # 18 p. 6918 - 6923
反应条件
Candida antarctica lipase B; hydrogen; nickel in toluene T=70°C; P=75.0075 Torr; 72 h; AutoclaveEnzymatic reaction; optical yield given as percent ee;
参考文献
Advanced Synthesis and Catalysis, , vol. 350, # 1 p. 113 - 121
反应条件
sodium tetrahydroborate; (S)-valinol; zirconium tetrachloride in tetrahydrofuran Ambient temperature; Title compound not separated from byproducts;
参考文献
Itsuno, Shinichi; Sakurai, Yoshiki; Shimizu, Koji; Ito, Koichi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 7 p. 1859 - 1863
反应条件
1: 80 percent / 4 Angstroem molecular sieves; Rh2[(S)-nttl]4; bis(tert-butylcarbonyloxy)iodobenzene / 1,1,2,2-tetrachloro-ethane; methanol / 72 h / -35 °C 2: Na; naphthalene / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 28 p. 4641 - 4644
