N-[(1,1-二甲基乙氧基)羰基]-L-缬氨酰-L-脯氨酸合成路线 (共 13 条)
反应条件
1.1: 99 percent / thionyl chloride / 4 h / 20 °C 2.1: isobutyl chloroformate; triethylamine / CH2Cl2 / 0.02 h / 0 °C 2.2: 31 percent / triethylamine / CH2Cl2 / 25 °C 3.1: 84 percent / lithium hydroxide monohydrate / methanol; H2O / 2 h / 25 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 12 p. 5006 - 5008
反应条件
1: 81.2 percent / HOBt; EDCI / dimethylformamide / 20 °C 2: 93.5 percent / aq. NaOH / methanol / 2 h / 20 °C View Scheme
参考文献
International Journal of Chemical Kinetics, , vol. 38, # 6 p. 376 - 385
反应条件
trifluoroacetic acid in dichloromethane T=0°C; 3 h;
参考文献
Arjmand, Farukh; Jamsheera; Mohapatra
Journal of Photochemistry and Photobiology B: Biology, 2013 , vol. 121, p. 75 - 85