(1S,2R)-2-氨基-1,2-二苯基乙醇合成路线 (共 40 条)
反应条件
triethylamine in dichloromethane T=0°C;
参考文献
Begis, Guillaume; Sheppard, Tom D.; Cladingboel, David E.; Motherwell, William B.; Tocher, Derek A.
Synthesis, 2005 , # 19 art. no. C06405SS, p. 3186 - 3188
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane 3 h;
参考文献
Simon, Monika; Micle, Andreea; Badea, Valentin; Csunderlik, Carol
Synthetic Communications, 2009 , vol. 39, # 15 p. 2633 - 2639
反应条件
potassium carbonate 8 h; Heating;
参考文献
Matsui, Satoshi; Hashimoto, Yukihiko; Saigo, Kazuhiko
Synthesis, 1998 , # 8 p. 1161 - 1166
反应条件
in tetrahydrofuran 3 h; Heating;
参考文献
Badone, Domenico; Bernassau, Jean-Marie; Cardamone, Rosanna; Guzzi, Umberto
Angewandte Chemie, 1996 , vol. 108, # 5 p. 575 - 578
反应条件
1: Et3N / tetrahydrofuran / 1 h / 20 °C 2: aq. NaHCO3 / CH2Cl2 / 1 h / 0 °C 3: p-TsOH*H2O / toluene View Scheme
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine 1.) THF, 2.) CH2Cl2, 3.) benzene, reflux; Yield given. Multistep reaction;
参考文献
Schuerman, Marla A.; Keverline, Kathryn I.; Hiskey, Richard G.
Tetrahedron Letters, 1995 , vol. 36, # 6 p. 825 - 828
反应条件
1: Et3N / tetrahydrofuran / 1 h / 20 °C 2: toluene / 10 h / Heating 3: p-TsOH*H2O / toluene View Scheme
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
1: ethanol 2: NaBH4 / ethanol View Scheme
参考文献
Jian, Li Sheng; Aiqiao, Mi; Guishu, Yang; Yaozhong, Jiang
Synthetic Communications, 1992 , vol. 22, # 10 p. 1497 - 1503
反应条件
sodium cyanoborohydride; acetic acid in methanol 3.5 h; pH 4;
参考文献
Ando; Tatematsu; Shioiri
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 8 p. 1967 - 1971
反应条件
triethylamine in tetrahydrofuran 18 h;
参考文献
Journal of the American Chemical Society, , vol. 110, # 5 p. 1547 - 1557