(1R,2r)-boc-2-氨基环己烷羧酸合成路线 （共 10 条）
反应条件
lithium hydroxide; dihydrogen peroxide in methanol T=20°C; 36 h;
参考文献
Raguse, Tami L.; Porter, Emilie A.; Weisblum, Bernard; Gellman, Samuel H.
Journal of the American Chemical Society, 2002 , vol. 124, # 43 p. 12774 - 12785
反应条件
sodium hydroxide in tetrahydrofuran; water
参考文献
Berkessel, Albrecht; Glaubitz, Katja; Lex, Johann
European Journal of Organic Chemistry, 2002 , # 17 p. 2948 - 2952
反应条件
2: 12 N aq. HCl / 48 h / Heating 3: aq. K2CO3 / dioxane / 5 h View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 26 p. 6206 - 6212
反应条件
1: 12 N aq. HCl / 48 h / Heating 2: aq. K2CO3 / dioxane / 5 h View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 26 p. 6206 - 6212
反应条件
1.1: acetyl chloride / Heating 1.2: NH3 gas / CH2Cl2 / 20 °C 1.3: 74 percent / phenyliodine(III) trifluoroacetate / acetonitrile; H2O / 20 °C 2.1: 68 percent / NaOH / tetrahydrofuran; H2O View Scheme
参考文献
European Journal of Organic Chemistry, , # 17 p. 2948 - 2952
反应条件
1.1: phenyliodine(III) bis(trifluoroacetate) / acetonitrile; H2O / 20 °C 1.2: 77 percent / cc. HCl 2.1: 68 percent / NaOH / tetrahydrofuran; H2O View Scheme
参考文献
European Journal of Organic Chemistry, , # 17 p. 2948 - 2952
反应条件
Multistep reaction.;
参考文献
Berkessel, Albrecht; Glaubitz, Katja; Lex, Johann
European Journal of Organic Chemistry, 2002 , # 17 p. 2948 - 2952
反应条件
1: HCl / dioxane / 1 h / 20 °C 2: 2.17 g / DIEA / acetonitrile / 0.5 h / 20 °C View Scheme
参考文献
Raguse, Tami L.; Porter, Emilie A.; Weisblum, Bernard; Gellman, Samuel H.
Journal of the American Chemical Society, 2002 , vol. 124, # 43 p. 12774 - 12785
反应条件
hydrogenchloride in 1,4-dioxane T=20°C; 1 h;
参考文献
Journal of the American Chemical Society, , vol. 124, # 43 p. 12774 - 12785
反应条件
hydrogenchloride in 1,4-dioxane T=20°C; 1 h;
参考文献
Journal of the American Chemical Society, , vol. 124, # 43 p. 12774 - 12785
