1-叔丁基-1H-吡咯-2-甲醛合成路线 （共 9 条）
反应条件
AlCl3 in 1,2-dichloro-ethane
参考文献
Emory University
Patent: US6441194 B1, 2002 ;
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate in anhydrous dichloroethane
Vilsmeier-Haack reaction; Reflux;
2: N-tert-butyl pyrrole in anhydrous dichloroethane
Vilsmeier-Haack reaction; 2 h; Reflux;
3: With water; sodium acetate
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
trichlorophosphate
Multistep reaction;
参考文献
Martinez, Gregory R.; Walker, Keith A. M.; Hirschfeld, Donald R.; Maloney, Patrick J.; Yang, Diana S.; Rosenkranz, Roberto P.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 4 p. 890 - 897
反应条件
1: With trichlorophosphate in anhydrous dichloroethane
Vilsmeier-Haack reaction; 1 h; Reflux;
2: With potassium hydroxide in anhydrous dichloroethane; water
0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane
Vilsmeier-Haack reaction; 1 h; Reflux;
2: With potassium hydroxide in anhydrous dichloroethane; water
0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane
Vilsmeier-Haack reaction; 1 h; Reflux;
2: With potassium hydroxide in anhydrous dichloroethane; water
0.0166667 h; regioselective reaction;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane
Vilsmeier-Haack reaction; 1 h; Reflux;
2: With potassium hydroxide in anhydrous dichloroethane; water
0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane
Vilsmeier-Haack reaction; 1 h; Reflux;
2: With potassium hydroxide in anhydrous dichloroethane; water
0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: With trichlorophosphate in anhydrous dichloroethane
Vilsmeier-Haack reaction; 1 h; Reflux;
2: With potassium hydroxide in anhydrous dichloroethane; water
0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
