(S)-(-)-2-氨基-3-甲基-1,1-二苯基丁烷合成路线 (共 3 条)
反应条件
hydrogen; acetic acid; palladium on activated charcoal in methanol P=2280 Torr; 48 h;
参考文献
O'Hagan, David; Tavasli, Mustafa
Tetrahedron Asymmetry, 1999 , vol. 10, # 6 p. 1189 - 1192
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in ethanol; n-heptane; trifluoroacetic acid T=0°C; Purification / work up;
参考文献
WO2010/148191 A2, ;
Page/Page column 45-49; 61 ;
反应条件
1: Et3N 2: 72 percent / H2, AcOH / 10 percent Pd/C / methanol / 48 h / 2280 Torr View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 6 p. 1189 - 1192