5-氟-2,3-二氢-1H-茚-2-胺合成路线 (共 1 条)
反应条件
1: With hydrogenchloride; n-Butyl nitrite in methanol T=40 - 55°C; 0.5 h; 2: With water; sodium hydrogencarbonate in ethyl acetate 3: With sodium hydroxide; sulfuric acid; water; hydrogen; acetic acid; palladium 10 on activated carbon more than 3 stages;
参考文献
Barvian, Kevin Karl; Speake, Jason Daniel; Cowan, David John; Larkin, Andrew Lamont; Szewczyk, Jerzy Ryszard
Patent: US2009/54431 A1, 2009 ;
Location in patent: Page/Page column 42 ;