9-苯基-9-硼杂双环[3.3.1]壬烷合成路线 （共 28 条）
反应条件
1: phenyl-(9-BBN) With lithium tert-butylate in 2-methyl-propan-1-ol; cyclohexane T=20°C; 0.333333 h; Schlenk techniqueInert atmosphere; 2: 1-adamantyl iodide With [(diglyme)NiBr2]; 4,4'-di-tert-butyl-2,2'-dipyridyl in 2-methyl-propan-1-ol; cyclohexane T=20 - 40°C; Suzuki Coupling; 28.5 h; Schlenk techniqueInert atmosphere;
参考文献
Zultanski, Susan L.; Fu, Gregory C.
Journal of the American Chemical Society, 2013 , vol. 135, # 2 p. 624 - 627
反应条件
1: 1-benzyl-tetrahydro-thiophenium tetrafluoroborate With lithium hexamethyldisilazane in tetrahydrofuran; dichloromethane T=-78°C; 1 h; 2: B-phenyl-(9-BBN) in tetrahydrofuran; dichloromethane T=-100 - 20°C; 3: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; dichloromethane T=20°C; 4 h; Further stages.;
参考文献
Journal of the American Chemical Society, , vol. 129, # 47 p. 14632 - 14639
反应条件
1: phenyl-(9-BBN) With lithium tert-butylate in 2-methyl-propan-1-ol; toluene T=20°C; 0.333333 h; Schlenk techniqueInert atmosphere; 2: 1-bromo-1-methylcyclohexane With [(diglyme)NiBr2]; 4,4'-di-tert-butyl-2,2'-dipyridyl in 2-methyl-propan-1-ol; toluene T=20 - 40°C; Suzuki Coupling; 28.5 h; Schlenk techniqueInert atmosphere;
参考文献
Journal of the American Chemical Society, , vol. 135, # 2 p. 624 - 627
反应条件
1,1-dimethylpropan-1-ol; ((Me)N2N)Ni-Cl; sodium iodide; sodium hydroxide in 1,4-dioxane T=80°C; Suzuki-Miyaura Coupling; 24 h; Inert atmosphere;
参考文献
Di Franco, Thomas; Boutin, Nicolas; Hu, Xile
Synthesis (Germany), 2013 , vol. 45, # 21 art. no. SS-2013-Z0609-FA, p. 2949 - 2958
反应条件
1,1-dimethylpropan-1-ol; ((Me)N2N)Ni-Cl; sodium iodide; sodium hydroxide in 1,4-dioxane T=80°C; Suzuki-Miyaura Coupling; 24 h; Inert atmosphere; SolventReagent/catalyst;
参考文献
Di Franco, Thomas; Boutin, Nicolas; Hu, Xile
Synthesis (Germany), 2013 , vol. 45, # 21 art. no. SS-2013-Z0609-FA, p. 2949 - 2958
反应条件
1: (4-methylphenyl)methyltetrahydrothiophenium tetrafluoroborate With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 2 h; 2: B-phenyl-(9-BBN) in tetrahydrofuran T=-110 - 0°C; 3: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran T=20°C; 8 h; Further stages.;
参考文献
Chemical Communications, , # 7 p. 741 - 743
反应条件
1,1-dimethylpropan-1-ol; ((Me)N2N)Ni-Cl; sodium iodide; sodium hydroxide in 1,4-dioxane
T=80°C; Suzuki-Miyaura Coupling; 24 h; Inert atmosphere;
参考文献
Di Franco, Thomas; Boutin, Nicolas; Hu, Xile
Synthesis (Germany), 2013 , vol. 45, # 21 art. no. SS-2013-Z0609-FA, p. 2949 - 2958
反应条件
1,1-dimethylpropan-1-ol; ((Me)N2N)Ni-Cl; sodium iodide; sodium hydroxide in 1,4-dioxane
T=80°C; Suzuki-Miyaura Coupling; 24 h; Inert atmosphere;
参考文献
Di Franco, Thomas; Boutin, Nicolas; Hu, Xile
Synthesis (Germany), 2013 , vol. 45, # 21 art. no. SS-2013-Z0609-FA, p. 2949 - 2958
反应条件
1: phenyl-(9-BBN) With lithium tert-butylate in 2-methyl-propan-1-ol; benzene
T=20°C; 0.333333 h; Schlenk techniqueInert atmosphere;
2: (3-bromo-3-methyl-n-butyl)benzene With [(diglyme)NiBr2]; 4,4'-di-tert-butyl-2,2'-dipyridyl in 2-methyl-propan-1-ol; benzene
T=20 - 40°C; Suzuki Coupling; 28.5 h; Schlenk techniqueInert atmosphere;
参考文献
Zultanski, Susan L.; Fu, Gregory C.
Journal of the American Chemical Society, 2013 , vol. 135, # 2 p. 624 - 627
反应条件
1,1-dimethylpropan-1-ol; ((Me)N2N)Ni-Cl; sodium iodide; sodium hydroxide in 1,4-dioxane
T=80°C; Suzuki-Miyaura Coupling; 24 h; Inert atmosphere;
参考文献
Di Franco, Thomas; Boutin, Nicolas; Hu, Xile
Synthesis (Germany), 2013 , vol. 45, # 21 art. no. SS-2013-Z0609-FA, p. 2949 - 2958
