N-[(1,1-二甲基乙氧基)羰基]-L-蛋氨酰-甘氨酸合成路线 （共 13 条）
反应条件
methanol; sodium hydroxide T=20°C; 3 h;
参考文献
Zhang, Jian; Li, Xiaoyang; Jiang, Yuqi; Feng, Jinhong; Li, Xiaoguang; Zhang, Yingjie; Xu, Wenfang
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 11 p. 3055 - 3064
反应条件
triethylamine in water; N,N-dimethyl-formamide Ambient temperature;
参考文献
Fukase; Kitazawa; Wakamiya; Shiba
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 6 p. 1838 - 1840
反应条件
phosphate buffer; oxygen; tyrosinase in water; acetonitrile T=20°C; pH=7.0; 12 h;
参考文献
Voelkert, Martin; Koul, Surrinder; Mueller, Gernot H.; Lehnig, Manfred; Waldmann, Herbert
Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 6902 - 6910
反应条件
triethylamine in water; N,N-dimethyl-formamide 16 h; Ambient temperature;
参考文献
Sakina; Kawazura; Morihara; Yajima
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 10 p. 3915 - 3919
反应条件
phosphate buffer; oxygen; tyrosinase in water; acetonitrile T=20°C; pH=7.0; 15 h;
参考文献
Voelkert, Martin; Koul, Surrinder; Mueller, Gernot H.; Lehnig, Manfred; Waldmann, Herbert
Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 6902 - 6910
反应条件
1: 83 percent / N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide; HOBt / CH2Cl2 / 0 - 20 °C 2: tyrosinase; phosphate buffer; O2 / acetonitrile; H2O / 15 h / 20 °C / pH 7.0 View Scheme
参考文献
Zhang, Jian; Li, Xiaoyang; Jiang, Yuqi; Feng, Jinhong; Li, Xiaoguang; Zhang, Yingjie; Xu, Wenfang
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 11 p. 3055 - 3064
反应条件
phosphate buffer; oxygen; tyrosinase in water; acetonitrile T=20°C; pH=7.0;
参考文献
Voelkert, Martin; Koul, Surrinder; Mueller, Gernot H.; Lehnig, Manfred; Waldmann, Herbert
Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 6902 - 6910
反应条件
phosphate buffer; oxygen; tyrosinase in water; acetonitrile T=20°C; pH=7.0;
参考文献
Voelkert, Martin; Koul, Surrinder; Mueller, Gernot H.; Lehnig, Manfred; Waldmann, Herbert
Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 6902 - 6910
反应条件
morpholine; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 1 h; Ambient temperature; Yield given;
参考文献
Schmittberger; Waldmann
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 5 p. 749 - 762
反应条件
2: dicyclohexylcarbodiimide 3: aqueous NaHCO3 / tetrahydrofuran; H2O View Scheme
参考文献
Lyons, Anthony Q.; Pettit, Leslie D.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1984 , p. 2305 - 2308
