4,5-二苯基-2-咪唑硫醇合成路线 (共 19 条)
反应条件
triethylamine in ethanol
7 h; Heating;
参考文献
Trzhtsinskaya, B.V.; Aleksandrova, A.E.; Abramova, N.D.; Andriyankova, L.V.; Vinogradova, T.I.; Shchegoleva, R.A.
Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 4 p. 346 - 349
Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 4 p. 57 - 60
参考文献
Anschuetz; Schwickerath
Justus Liebigs Annalen der Chemie, 1895 , vol. 284, p. 20
反应条件
triethylamine in ethanol
0.0333333 h; Microwave irradiation;
参考文献
Aouad, Mohamed R.; Rezki, Nadjet; El Ahsry, El Sayed H.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1321 - 1327
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=20°C; 48 h; Inert atmosphere;
参考文献
Moore, Terry W.; Sana, Kasinath; Yan, Dan; Krumm, Stefanie A.; Thepchatri, Pahk; Snyder, James P.; Marengo, Jose; Arrendale, Richard F.; Prussia, Andrew J.; Natchus, Michael G.; Liotta, Dennis C.; Plemper, Richard K.; Sun, Aiming
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 8 p. 762 - 767
反应条件
sodium hydroxide
1.) ethanol, heating, 2.) ethanol; Yield given. Multistep reaction;
参考文献
Mathew; Purushothaman
Journal of the Indian Chemical Society, 1991 , vol. 68, # 12 p. 670 - 672
参考文献
Sharpe, Thomas R.; Cherkofsky, Saul C.; Hewes, Walter E.; Smith, Dewey H.; Gregory, Walter A.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1188 - 1194
反应条件
potassium carbonate
1.) DMF, RT, 30 min, 2.) DMF, RT, overnight; Yield given. Multistep reaction;
参考文献
Harris, Neil V.; Smith, Christopher; Asthon, Michael J.; Bridge, Andrew W.; Bush, Raymond C.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 23 p. 4384 - 4392
反应条件
hydrogenchloride
2 h; Heating;
参考文献
Abramova, N. D.; Skvortsova, G. G.; Trzhtsinskaya, B. V.
Journal of Organic Chemistry USSR (English Translation), 1984 , p. 1854
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 9 p. 2031 - 2032
反应条件
triethylamine in toluene
Heating;
参考文献
Sharpe, Thomas R.; Cherkofsky, Saul C.; Hewes, Walter E.; Smith, Dewey H.; Gregory, Walter A.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1188 - 1194