4,4'-二(羟基甲基)二苯基醚合成路线 （共 8 条）
反应条件
phosphorus tribromide in tetrahydrofuran; toluene T=20°C;
参考文献
Gibson, Harry W.; Wang, Hong; Niu, Zhenbin; Slebodnick, Carla; Zhakharov, Lev N.; Rheingold, Arnold L.
Macromolecules, 2012 , vol. 45, # 3 p. 1270 - 1280
反应条件
pyridinium chlorochromate in dichloromethane 2 h; Molecular sieveInert atmosphereReflux;
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=0°C; 72 h;
参考文献
Shimizu, Linda S.; Hughes, Andrew D.; Smith, Mark D.; Davis, Matthew J.; Zhang, B. Paul; Zur Loye, Hans-Conrad; Shimizu, Ken D.
Journal of the American Chemical Society, 2003 , vol. 125, # 49 p. 14972 - 14973
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
Inert atmosphereCooling with iceReflux;
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
反应条件
1: copper(l) iodide; N,N-dimethylaminoacetic acid; caesium carbonate / 1,4-dioxane / 24 h / Reflux; Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Cooling with ice; Reflux
View Scheme
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
反应条件
1: copper(l) iodide; N,N-dimethylaminoacetic acid; caesium carbonate / 1,4-dioxane / 24 h / Reflux; Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Cooling with ice; Reflux
View Scheme
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
反应条件
1: sulfuric acid / 4 h / Reflux
2: copper(l) iodide; N,N-dimethylaminoacetic acid; caesium carbonate / 1,4-dioxane / 24 h / Reflux; Inert atmosphere
3: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Cooling with ice; Reflux
View Scheme
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
反应条件
1: sulfuric acid / 5 h / Reflux
2: copper(l) iodide; N,N-dimethylaminoacetic acid; caesium carbonate / 1,4-dioxane / 24 h / Reflux; Inert atmosphere
3: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Cooling with ice; Reflux
View Scheme
参考文献
Gurung, Santosh K.; Kim, Soo Bae; Park, Haeil
Archives of Pharmacal Research, 2010 , vol. 33, # 12 p. 1919 - 1926
