9-丁基-9-硼杂双环[3.3.1]壬烷合成路线 （共 15 条）
反应条件
1: in tetrahydrofuran T=0°C; Alkylation; Grignard-reaction; 0.75 h; 2: T=105 - 110°C; Decomposition; P=3 Torr;
参考文献
Soderquist, John A.; Justo De Pomar, Jorge C.
Tetrahedron Letters, 2000 , vol. 41, # 19 p. 3537 - 3539
反应条件
1: in diethyl ether T=-78°C; Alkylation; 0.75 h; 2: T=100°C; Decomposition; P=0.3 Torr;
参考文献
Soderquist, John A.; Justo De Pomar, Jorge C.
Tetrahedron Letters, 2000 , vol. 41, # 19 p. 3537 - 3539
反应条件
in pentane T=0 - 20°C;
参考文献
Medina, Jesus R.; Cruz, Gabriel; Cabrera, Carlos R.; Soderquist, John A.
Journal of Organic Chemistry, 2003 , vol. 68, # 12 p. 4631 - 4642
反应条件
in diethyl ether byproducts: Cu, Li, C4H10; to the soln. of copper(I) iodide/ether n-butyl-lithium was added at 0°C, stirred for 10 min, cooled to -78°C, 9-BBN was added, allowed to warm to room temp, stirred for 1 h; decanted off, evapd. in vac., distd.;
参考文献
Whiteley, Chris G.
Journal of the Chemical Society, Chemical Communications, 1981 , # 1 p. 5 - 6
反应条件
in hexane; pentane T=-78 - -20°C; Alkylation;
参考文献
O'Donnell, Martin J.; Delgado, Francisca; Drew, Mark D.; Pottorf, Richard S.; Zhou, Changyou; Scott, William L.
Tetrahedron Letters, 1999 , vol. 40, # 32 p. 5831 - 5835
反应条件
1.1: 85 percent / 12 h / 135 - 150 °C 2.1: tetrahydrofuran / 0.75 h / 0 °C 2.2: 82 percent / 105 - 110 °C / 3 Torr View Scheme
参考文献
Soderquist, John A.; Justo De Pomar, Jorge C.
Tetrahedron Letters, 2000 , vol. 41, # 19 p. 3537 - 3539
反应条件
in further solvent(s) byproducts: H2, CH4, C2H6; a suspension of 9-BBN and Fe3(CO)12 in nonane was slowly heated to above 130°C (bath temp.) under an inert gas atm.; stirring for about 0.5 h; further products and byproducts; mechanism discussed;; distn. under vac.; mixt. of 9-alkyl-9-BBN obtained, detected by GC/MS;;
参考文献
Koester, Roland; Yalpani, Mohamed
Angewandte Chemie, 1985 , vol. 97, p. 600 - 602
反应条件
in further solvent(s) byproducts: H2, CH4, C4H10; a suspension of 9-BBN and Fe(CO)5 in nonane was slowly heated to about 140°C (bath temp.) under an inert gas atm.; stirring for about 0.5 h; further products and byproducts; mechanism discussed;; distn. under vac.; mixt. of 9-alkyl-9-BBN obtained, detected by GC/MS;;
参考文献
Koester, Roland; Yalpani, Mohamed
Angewandte Chemie, 1985 , vol. 97, p. 600 - 602
反应条件
in further solvent(s) byproducts: H2, CH4, C2H6; a suspension of 9-BBN and Fe2(CO)9 in nonane was slowly heated to above140°C (bath temp.) under an inert gas atm.; stirring for about 0.5 h; further products and byproducts; mechanism discussed;; distn. under vac.; mixt. of 9-alkyl-9-BBN obtained, detected by GC/MS;;
参考文献
Koester, Roland; Yalpani, Mohamed
Angewandte Chemie, 1985 , vol. 97, p. 600 - 602
反应条件
in further solvent(s) byproducts: H2, CH4, C2H6; a suspension of 9-BBN and Co2(CO)8 in nonane was slowly heated to above90°C (bath temp.) under an inert gas atm.; stirring for about 0.5 h; further products and byproducts; mechanism discussed;; distn. under vac.; mixt. of 9-alkyl-9-BBN obtained, detected by GC/MS;;
参考文献
Koester, Roland; Yalpani, Mohamed
Angewandte Chemie, 1985 , vol. 97, p. 600 - 602
