1: bromocyane / dichloromethane / 12 h / 20 °C / Inert atmosphere 2: water; toluene / 6 h / 0 - 20 °C 3: dichloromethane / 12 h / Inert atmosphere; Reflux View Scheme

bromocyane in dichloromethane T=20°C; 12 h; Inert atmosphere;

1: 30percent H2O2 / ethanol; CH2Cl2 / 28 h / 62 °C 2: 1.) trifluoroacetic anhydride, 2.) NaOAc / 1.) CH2Cl2, 0 deg C, 1h, then room temp., 15 min, 2.) H2O, room temp., 30 min View Scheme