柔红霉素盐酸盐合成路线

参考文献

Nucleosides and Nucleotides, , vol. 16, # 1-2 p. 87 - 95

79867-79-16,9,11-三羟基-9-(1-羟基乙基)-7-[(4S,5S,6S)-5-羟基-6-甲基-4-吗啉-4-基四氢吡喃-2-基]氧基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮+

参考文献

Mosher, Carol W.; Wu, Helen Y.; Fujiwara, Allan N.; Acton, Edward M.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 18 - 24

23541-50-6柔红霉素盐酸盐

21794-55-8柔红酮+

79867-79-16,9,11-三羟基-9-(1-羟基乙基)-7-[(4S,5S,6S)-5-羟基-6-甲基-4-吗啉-4-基四氢吡喃-2-基]氧基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮+

79867-78-03'-(4-吗啉基)-3'-去氨基柔红霉素

参考文献

Mosher, Carol W.; Wu, Helen Y.; Fujiwara, Allan N.; Acton, Edward M.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 18 - 24

23541-50-6柔红霉素盐酸盐

32384-98-8(8R)-8-乙酰基-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌

参考文献

Brand, David J.; Fisher, Jed
Journal of the American Chemical Society, 1986 , vol. 108, # 11 p. 3088 - 3096

23541-50-6柔红霉素盐酸盐

118868-84-1+

32384-98-8(8R)-8-乙酰基-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌

参考文献

Bird; Gaudiano; Koch
Journal of the American Chemical Society, 1991 , vol. 113, # 1 p. 308 - 315

23541-50-6柔红霉素盐酸盐

25316-40-9盐酸多柔比星

参考文献

Horton, Derek; Priebe, Waldemar; Sznaidman, Marcos
Carbohydrate Research, 1988 , vol. 184, p. 231 - 235

23541-50-6柔红霉素盐酸盐+

3190-70-3(S)-(-)-4-异丁基氧氮杂环戊烷-2,5-二酮

66900-32-1

参考文献

Masquelier; Baurain; Trouet
Journal of Medicinal Chemistry, 1980 , vol. 23, # 11 p. 1166 - 1170

参考文献

Mosher, Carol W.; Wu, Helen Y.; Fujiwara, Allan N.; Acton, Edward M.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 1 p. 18 - 24

7456-83-92,2'-氧基二乙醛+

23541-50-6柔红霉素盐酸盐

79867-79-16,9,11-三羟基-9-(1-羟基乙基)-7-[(4S,5S,6S)-5-羟基-6-甲基-4-吗啉-4-基四氢吡喃-2-基]氧基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮+

79867-78-03'-(4-吗啉基)-3'-去氨基柔红霉素+

89164-75-0+

89617-36-73-乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基3-(3-氰基-4-吗啉基)-2,3,6-三脱氧吡喃己糖苷

参考文献

Acton; Tong; Mosher; Wolgemuth
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 638 - 645

7456-83-92,2'-氧基二乙醛+

23541-50-6柔红霉素盐酸盐+

75-05-8乙腈

79867-79-16,9,11-三羟基-9-(1-羟基乙基)-7-[(4S,5S,6S)-5-羟基-6-甲基-4-吗啉-4-基四氢吡喃-2-基]氧基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮+

79867-78-03'-(4-吗啉基)-3'-去氨基柔红霉素+

89164-75-0+

89617-36-73-乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基3-(3-氰基-4-吗啉基)-2,3,6-三脱氧吡喃己糖苷

参考文献

Acton; Tong; Mosher; Wolgemuth
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 638 - 645