2-溴-N-甲基-4'-硝基乙酰苯胺合成路线 （共 4 条）
反应条件
potassium carbonate in acetone T=20°C; 3 h;
参考文献
Roth, Gerald J.; Heckel, Armin; Colbatzky, Florian; Handschuh, Sandra; Kley, Joerg; Lehmann-Lintz, Thorsten; Lotz, Ralf; Tontsch-Grunt, Ulrike; Walter, Rainer; Hilberg, Frank
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4466 - 4480
反应条件
in dimethyl sulfoxide
T=25°C; Kinetics;
参考文献
Adhikary, Keshab Kumar; Lee, Hai Whang
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 3 p. 857 - 862
反应条件
1: 82 percent / toluene / 12 h / Ambient temperature
2: 1) K-O-tBu / 1) THF, 1 h, RT
3: 10 percent / xylene / 50 h / Heating
View Scheme
参考文献
Diehl, Klaus; Himbert, Gerhard; Henn, Lothar
Chemische Berichte, 1986 , vol. 119, # 8 p. 2430 - 2443
反应条件
Multi-step reaction with 2 steps 1: 82 percent / toluene / 12 h / Ambient temperature2: 1) K-O-tBu / 1) THF, 1 h, RT
参考文献
Diehl, Klaus; Himbert, Gerhard; Henn, Lothar Chemische Berichte, 1986 , vol. 119, # 8 p. 2430 - 2443
