(20E)-3beta-羟基孕甾-5,16-二烯-20-酮 20-肟 3-乙酸酯合成路线 （共 11 条）
反应条件
potassium hydroxide in methanol T=70°C; 0.166667 h;
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 22 p. 4266 - 4277
反应条件
1: phosphorus(III) oxychloride 2: potassium hydroxide / methanol 3: pyridine / 8 h / Heating 4: Reflux View Scheme
参考文献
Dhingra, Neelima; Bhardwaj; Mehta, Neeraj; Mukhopadhyay, Tapas; Kumar, Ashok; Kumar, Manoj
Archives of Pharmacal Research, 2011 , vol. 34, # 7 p. 1055 - 1063
反应条件
1: aq. Pb(OAc)4, I2 / benzene / Heating 2: Zn, AcOH / Heating View Scheme
参考文献
Kaufmann,S. et al.
Journal of Organic Chemistry, 1969 , vol. 34, # 6 p. 1618 - 1621
反应条件
1.1: POCl3; pyridine / toluene / 4 h / 10 - 20 °C 1.2: 51.8 percent / KOH / methanol / Heating 2.1: 40.9 percent / Mucor racemosus / acetone / 96 h / 27 °C View Scheme
参考文献
Li, Heping; Liu, Hong-Min; Ge, Wenzhong; Huang, Lihua; Shan, Lihong
Steroids, 2005 , vol. 70, # 14 p. 970 - 973
反应条件
1: trichlorophosphate 2: hydroxylamine hydrochloride View Scheme
参考文献
Dhingra, Neelima; Bhardwaj, Tilak Raj; Mehta, Neeraj; Mukhopadhyay, Tapas; Kumar, Ashok; Kumar, Manoj
Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 817 - 825
反应条件
1: With pyridine; trichlorophosphate in toluene T=10 - 20°C; Bechmanns' reaction; 4 h; 2: With potassium hydroxide in methanol Heating;
参考文献
Li, Heping; Liu, Hong-Min; Ge, Wenzhong; Huang, Lihua; Shan, Lihong
Steroids, 2005 , vol. 70, # 14 p. 970 - 973
参考文献
Dhingra, Neelima; Bhardwaj; Mehta, Neeraj; Mukhopadhyay, Tapas; Kumar, Ashok; Kumar, Manoj
Archives of Pharmacal Research, 2011 , vol. 34, # 7 p. 1055 - 1063
反应条件
und anschliessend mit Eis und wss.H2SO4;
参考文献
Rosenkranz et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 520
反应条件
und Behandeln des Reaktionsgemisches mit wss.H2SO4;
参考文献
Parke,Davis and Co.
Patent: US2335616 , 1941 ;
反应条件
Dess-Martin periodane in dichloromethane; water 0.333333 h;
参考文献
Chaudhari, Sachin S.; Akamanchi, Krishnacharya G.
Tetrahedron Letters, 1998 , vol. 39, # 20 p. 3209 - 3212
