3-O-苄基-1,2-O-异亚丙基-Alpha-D-木质二醛糖合成路线 （共 22 条）
参考文献
Danishefsky, Samuel J.; DeNinno, Michael P.; Phillips, Gary B.; Zelle, Robert E.
Tetrahedron, 1986 , vol. 42, # 11 p. 2809 - 2819
反应条件
1: 70 percent / tetrahydrofuran / 2 h / -20 °C 2: 5 percent / NaOAc, NaBr, CH3CO3H / acetic acid / 2 h / 0 °C View Scheme
参考文献
Smid, P.; Schipper, F. J. M.; Broxterman, H. J. G.; Boons, G. J. P. H.; Marel, G. A. van der; Boom, J. H. van
Recueil des Travaux Chimiques des Pays-Bas, 1993 , vol. 112, # 7-8 p. 451 - 456
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
ISIS PHARMACEUTICALS, INC.; SETH, Punit, P.; SWAYZE, Eric, E.; HANESSIAN, Stephen; SCHROEDER, Benjamin, R.; GIACOMETTI, Robert, D.; MERNER, Bradley, L.
Patent: WO2013/154798 A1, 2013 ;
Location in patent: Page/Page column 68 ;
反应条件
sodium hydroxide in tetrahydrofuran; water T=25°C; 10 h;
参考文献
Tetrahedron, , vol. 60, # 19 p. 4275 - 4281
反应条件
sodium periodate in 1,4-dioxane
2 h;
参考文献
Bonnaffe, David; Lubineau, Andre; Alais, Jocelyne; Gavard, Olivier; Dilhas, Anna; Lortat-Jacob, Hugues
Patent: US2006/166927 A1, 2006 ;
Location in patent: Page/Page column 21 ;
反应条件
acetic acid; periodic acid in water
0.416667 h; Ambient temperature;
参考文献
Kirihata, Mitsunori; Ohta, Kazunari; Ichimoto, Itsuo; Ueda, Hiroo
Agricultural and Biological Chemistry, 1990 , vol. 54, # 9 p. 2401 - 2405
反应条件
1: With acetic acid
T=70°C; 3 h;
2: With sodium periodate; silica gel in dichloromethane
T=20°C; 2 h; Further stages.;
参考文献
Chincholkar; Puranik, Vedavati G.; Deshmukh
Tetrahedron, 2007 , vol. 63, # 37 p. 9179 - 9187
反应条件
sodium periodate; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate in dichloromethane; water
T=0 - 20°C; 4 h;
参考文献
Hsu, Ching-Yun; Lee, I-Chi; Lico, Larry S.; Uang, Biing-Jiun; Hung, Shang-Cheng
Journal of the Chinese Chemical Society, 2012 , vol. 59, # 3 p. 421 - 425
反应条件
1: NaH; tetrabutylammonium iodide / tetrahydrofuran / 14 h / 20 °C
2: 17.8 g / acetic acid / H2O / 16 h / 20 °C
3: sodium periodate; silica gel / CH2Cl2; H2O / 1.5 h
View Scheme
参考文献
Lohman, Gregory J. S.; Hunt, Diana K.; Hoegermeier, Jens A.; Seeberger, Peter H.
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7559 - 7561
反应条件
1: (n-But)4NI,NaH / tetrahydrofuran
2: 0.8 percent H2SO4 / methanol / 24 h
3: NaI4 / dioxane; H2O
View Scheme
参考文献
Anderson, R.C.; Nabinger, R.C.
Tetrahedron Letters, 1983 , vol. 24, # 27 p. 2741 - 2744
