3-O-苄基-1,2-O-异亚丙基-Alpha-D-木质二醛糖合成路线 (共 22 条)
反应条件
1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane
0.5 h;
2: (3aR,5S,6S,6aR)-6-(benzyloxy)-tetrahydro-2,2-dimethylfuro[2,3-d][1,3]dioxol-5-carbaldehyde in tetrahydrofuran; hexane
T=0°C; 3 h; Inert atmosphere;
参考文献
Hsu, Ching-Yun; Lee, I-Chi; Lico, Larry S.; Uang, Biing-Jiun; Hung, Shang-Cheng
Journal of the Chinese Chemical Society, 2012 , vol. 59, # 3 p. 421 - 425
反应条件
1: (tributylstannyl)methyl 2,4,6-triisopropylbenzoate With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.0833333 h; Inert atmosphere;
2: (3aR,5S,6S,6aR)-6-(benzyloxy)-tetrahydro-2,2-dimethylfuro[2,3-d][1,3]dioxol-5-carbaldehyde in tetrahydrofuran; hexane
T=-78°C; 0.5 h; Inert atmosphere;
3: With water; sodium hydrogencarbonate in tetrahydrofuran; hexane
T=-78°C; Inert atmosphere; optical yield given as percent de;
参考文献
Kapeller, Dagmar C.; Hammerschmidt, Friedrich
Tetrahedron, 2010 , vol. 66, # 3 p. 591 - 598