3-(n-苄胺)丙酸甲酯合成路线 (共 24 条)
反应条件
T=100 - 110°C; 168 h; sealed tube;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 9 p. 2525 - 2530
反应条件
1: 91 percent / K2CO3 / CHCl3 / 7.5 h / Heating 2: 1) C2H5OK, 2) HCl / 1) ethanol, xylene, reflux, 16 h; 2) ethanol. View Scheme
参考文献
Polivka, Zdenek; Metys, Jan; Protiva, Miroslav
Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 9 p. 2034 - 2049
反应条件
1: With thien-2-yl-lithium in tetrahydrofuran
T=-78°C; 0.5 h;
2: With acetic acid in tetrahydrofuran
参考文献
Lima, Paulo G.; Sequeira, Lucia C.; Costa, Paulo R.R.
Tetrahedron Letters, 2001 , vol. 42, # 21 p. 3525 - 3527
反应条件
diethyl ether; sodium methylate
参考文献
Southwick; Crouch
Journal of the American Chemical Society, 1953 , vol. 75, p. 3413,3416