2,4-二甲基苯甲酸甲酯合成路线 （共 25 条）
反应条件
hydrazine in methanol
40 h; Heating / reflux;
参考文献
Tachdjian, Catherine; Lebl-Rinnova, Marketa; Wallace, David
Patent: US2006/263411 A1, 2006 ;
Location in patent: Page/Page column 40 ;
反应条件
1: NBS, benzoyl peroxide / CCl4 / 3 h / Heating
2: 1 h / 180 °C / 10 Torr
3: 83 percent / H2, Ca(OH)2 / 10percent Pd/C / dioxane / 48 h / 2068.6 Torr
4: 1.) NBS, benzoyl peroxide, 2.) H2O / 1.) CCl4, reflux, 1 h, 2.) reflux
View Scheme
参考文献
Neudeck
Monatshefte fur Chemie, 1996 , vol. 127, # 2 p. 201 - 217
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane
3.5 h; Heating;
参考文献
Dawson; Hobbs; Chan; Chao; Fung
Journal of Medicinal Chemistry, 1981 , vol. 24, # 5 p. 583 - 592
反应条件
1: NBS, benzoyl peroxide / CCl4 / 3 h / Heating
2: 1 h / 180 °C / 10 Torr
3: 83 percent / H2, Ca(OH)2 / 10percent Pd/C / dioxane / 48 h / 2068.6 Torr
View Scheme
参考文献
Neudeck
Monatshefte fur Chemie, 1996 , vol. 127, # 2 p. 201 - 217
反应条件
Sodium bromate; sodium hydrogensulfite
参考文献
Edgar, Dale M.; Hangauer, David G.; White, James F.; Solomon, Michael
Patent: US2005/143348 A1, 2005 ;
Location in patent: Page/Page column 50 ;
US 20050143348 A1
