2'-C-甲基尿苷 2',3',5'-三苯甲酸酯合成路线 （共 5 条）
反应条件
1: 87 percent / CH3ONa; methanol / 20 °C View Scheme
参考文献
Pierra; Benzaria; Amador; Moussa; Mathieu; Storer; Gosselin
Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 767 - 770
反应条件
ammonia in methanol T=0 - 4°C; 48 h;
参考文献
Li, Nan-Sheng; Piccirilli, Joseph A.
Journal of Organic Chemistry, 2003 , vol. 68, # 17 p. 6799 - 6802
反应条件
1: 100 percent / ammonia gas / methanol / 48 h / 0 - 4 °C
2: 65 percent / imidazole / dimethylformamide / 2 h / 20 °C
3: DMAP / acetonitrile / 1 h / 20 °C
4: 0.502 g / 2,2'-azobisisobutyronitrile; tributyltin hydride / toluene / 2 h / Heating
5: triethylamine; DMAP / acetonitrile / 53 h / 20 °C
6: 0.337 g / ammonium hydroxide / H2O; acetonitrile / 3 h / 20 °C
7: TBAF / tetrahydrofuran / 1 h / 20 °C
View Scheme
参考文献
Li, Nan-Sheng; Piccirilli, Joseph A.
Journal of Organic Chemistry, 2003 , vol. 68, # 17 p. 6799 - 6802
反应条件
Multi-step reaction with 2 steps 1: 1.) CeCl3, 2.) DMAP, Et3N2: bis(trimethylsilyl)acetamide, SnCl4 / acetonitrile / 3 h / Heating
参考文献
Harry-O'kuru, Rogers E.; Kryjak, Emily A.; Wolfe, Michael S. Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1457 - 1460
反应条件
Multi-step reaction with 2 steps 1: 1.) CeCl3, 2.) DMAP, Et3N2: bis(trimethylsilyl)acetamide, SnCl4 / acetonitrile / 3 h / Heating
参考文献
Harry-O'kuru, Rogers E.; Kryjak, Emily A.; Wolfe, Michael S. Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1457 - 1460
