巯基乙酸甲酯合成路线

GENENTECH,INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Kanl H.; DRAGOVICH, Peter; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; YUEN, Po-Wai; ZAK, Mark; ZHANG, Yamin; ZHENG, Xiaozhang; ZHAO, Guiling
Patent: WO2013/127268 A1, 2013 ;
Location in patent: Page/Page column 64; 65 ;

145325-40-24-溴噻吩并[2,3-C]吡啶-2-甲醛

参考文献

GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth, W.; BAUMEISTER, Timm, R.; BUCKMELTER, Alexandre, J.; CLODFELTER, Karl, H.; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; REYNOLDS, Dominic, J.; SMITH, Chase, C.; WANG, Zhongguo; ZAK, Mark; ZHENG, Xiaozhang; ZHAO, Guiling
Patent: WO2013/130943 A1, 2013 ;
Location in patent: Paragraph 0196 ;

60611-24-72-氟-6-(三氟甲基)苯甲醛+

2365-48-2巯基乙酸甲酯

146137-87-34-(三氟甲基)-1-苯并噻吩-2-羧酸甲酯

参考文献

SUMITOMO CHEMICAL COMPANY, LIMITED; MUKUMOTO, Fujio; TAMAKI, Hiroaki; IWAKOSHI, Mitsuhiko; KUSAKA, Shintaro
Patent: WO2012/153861 A1, 2012 ;
Location in patent: Page/Page column 23 ;

2365-48-2巯基乙酸甲酯+

107-13-1丙烯腈

16563-14-74-氰基-3-四氢噻吩酮

参考文献

Synthesis, , # 10 p. 969 - 970

2365-48-2巯基乙酸甲酯+

146137-78-22-氟-5-(三氟甲基)苯甲醛

146137-92-05-三氟甲基苯并[b]噻吩-2-羧酸甲酯

参考文献

SUMITOMO CHEMICAL COMPANY, LIMITED; MUKUMOTO, Fujio; TAMAKI, Hiroaki; IWAKOSHI, Mitsuhiko; KUSAKA, Shintaro
Patent: WO2012/153861 A1, 2012 ;
Location in patent: Page/Page column 20-21 ;

2646-90-42,5-二氟苯甲醛+

2365-48-2巯基乙酸甲酯

154630-32-75-氟苯并[b]噻吩-2-羧酸甲酯

参考文献

NOVARTIS AG; Bock, Mark Gary; Gaul, Christoph; Gummadi, Venkateshwar Rao; Moebitz, Henrik; Sengupta, Saumitra
Patent: US2014/45872 A1, 2014 ;
Location in patent: Paragraph 0827 ;