lithium carbonate; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; Heating;

pyridine 3 h; Ambient temperature;

1: tetrafluoroboric acid / water / 0.67 h / Cooling with ice 2: lithium carbonate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Heating View Scheme

1: sodium hydroxide / tetrahydrofuran; water / 1.5 h / 20 °C 2: 80 °C / Cooling with ice 3: tetrafluoroboric acid / water / 0.67 h / Cooling with ice 4: lithium carbonate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Heating View Scheme

1: 80 °C / Cooling with ice 2: tetrafluoroboric acid / water / 0.67 h / Cooling with ice 3: lithium carbonate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Heating View Scheme

1: triethylamine / acetonitrile / 0 - 5 °C 2: POCl3; N-methylpyrrolidine / acetonitrile 3: NH3 / H2O; dioxane / 20 °C View Scheme