1-(4-联苯基)-2,2,2-三氟乙酮合成路线 （共 9 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in water; isopropyl alcohol T=110°C; Suzuki-Miyaura Coupling; 0.0833333 h; Microwave irradiation;
参考文献
De Oliveira Lopes, Raquel; De Miranda, Amanda S.; Reichart, Benedikt; Glasnov, Toma; Kappe, C. Oliver; Simon, Robert C.; Kroutil, Wolfgang; Miranda, Leandro S.M.; Leal, Ivana C.R.; De Souza, Rodrigo O.M.A.
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 104, p. 101 - 107
反应条件
aluminium trichloride in dichloromethane T=20°C; 1 h;
参考文献
Wang, Jin; Kubicki, Jacek; Gustafson, Terry L.; Platz, Matthew S.
Journal of the American Chemical Society, 2008 , vol. 130, # 7 p. 2304 - 2313
反应条件
Triethylgermyl-natrium in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide T=-60°C; 1.5 h;
参考文献
Yokoyama, Yasuo; Mochida, Kunio
Synlett, 1997 , vol. 1997, # 8 p. 907 - 908
反应条件
1: trifluoroacetic acid With bromine; magnesium in diethyl ether T=20°C; Metallation; 1.5 h; 2: 4-(phenyl)-phenylmagnesium bromide in diethyl ether Grignard reaction; 1 h; Heating;
参考文献
Uno, Hidemitsu; Nibu, Nobumasa; Misobe, Noboru
Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 6 p. 1365 - 1375
反应条件
carbon disulfide; aluminium trichloride T=5°C;
参考文献
Saunders; Slocombe; Hardy
Journal of the American Chemical Society, 1949 , vol. 71, p. 752
反应条件
n-butyllithium in diethyl ether T=-78°C;
参考文献
Fujisawa, Tamotsu; Onogawa, Yoshio; Sato, Akira; Mitsuya, Takeshi; Shimizu, Makoto
Tetrahedron, 1998 , vol. 54, # 17 p. 4267 - 4276
反应条件
triphenylphosphine in diethylene glycol dimethyl ether
参考文献
Naae,D.G.
Journal of Organic Chemistry, 1977 , vol. 42, # 10 p. 1780 - 1783
反应条件
1: Ph3P / bis-(2-methoxy-ethyl) ether
2: Br2
View Scheme
参考文献
Naae,D.G.
Journal of Organic Chemistry, 1977 , vol. 42, # 10 p. 1780 - 1783
反应条件
1: Ph3P / bis-(2-methoxy-ethyl) ether
2: Br2 / 1,1,2-trichloro-1,2,2-trifluoro-ethane
View Scheme
参考文献
Naae,D.G.
Journal of Organic Chemistry, 1977 , vol. 42, # 10 p. 1780 - 1783
