1-(2-(苯基氨基)苯基)乙酮合成路线 （共 14 条）
反应条件
selenium(IV) oxide in 1,4-dioxane T=80°C; 24 h; Reagent/catalystSolventTemperature;
参考文献
Liu, Yong; Chen, Hui; Hu, Xiong; Zhou, Wang; Deng, Guo-Jun
European Journal of Organic Chemistry, 2013 , # 20 p. 4229 - 4232
反应条件
1: 85 percent / NH2OH*HCl, pyridine / ethanol / 1 h / Heating 2: 63 percent / NaOH / H2O / 16 h / Heating 3: 1.) CDI / 1.) THF, r.t., 1 h, 2.) THF, light petroleum, 0-5 deg C, 4 h 4: 23 percent / various solvent(s) / 1 h / Heating View Scheme
参考文献
Calestani, Gianluca; Leardini, Rino; McNab, Hamish; Nanni, Daniele; Zanardi, Giuseppe
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 11 p. 1813 - 1824
反应条件
1: 82 percent / pyridine / ethanol / 6 h / Heating 2: 92 percent / 650 °C / 0.01 Torr View Scheme
参考文献
Leardini, Rino; McNab, Hamish; Nanni, Daniele; Parsons, Simon; Reed, David; Tenan, Anton G.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 11 p. 1833 - 1838
反应条件
pyridine; copper diacetate in dichloromethane
T=20°C;
参考文献
Greenbaum, Doron C.; Mackey, Zachary; Hansell, Elizabeth; Doyle, Patricia; Gut, Jiri; Caffrey, Conor R.; Lehrman, Julia; Rosenthal, Philip J.; McKerrow, James H.; Chibale, Kelly
Journal of Medicinal Chemistry, 2004 , vol. 47, # 12 p. 3212 - 3219
反应条件
palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl
T=120°C; 12 h;
参考文献
Wei, Wen-Tao; Dong, Xue-Jiao; Nie, Shao-Zhen; Chen, Yan-Yan; Zhang, Xue-Jing; Yan, Ming
Organic Letters, 2013 , vol. 15, # 23 p. 6018 - 6021
反应条件
copper; potassium carbonate in anhydrous butyl ether
22 h; Heating;
参考文献
Hellwinkel, Dieter; Ittemann, Peter
Chemische Berichte, 1986 , vol. 119, # 10 p. 3165 - 3197
反应条件
aniline in ethanol; dichloromethane; water; sodium carbonate
参考文献
Novartis Finance Corp.
Patent: US5869485 A1, 1999 ;
US 5869485 A
反应条件
1: 2-(N-phenylamino)benzoic acid With lithium hydride in tetrahydrofuran
0.5 h; Heating;
2: methyllithium in tetrahydrofuran; diethyl ether
T=20°C; 4 h;
参考文献
Usachev, Boris I.; Sosnovskikh, Vyacheslav Ya.
Journal of Fluorine Chemistry, 2004 , vol. 125, # 9 p. 1393 - 1395
参考文献
Warner-Lambert Company
Patent: US5153226 A1, 1992 ;
反应条件
1: (i) nBuLi, (ii) /BRN= 605303/
2: benzene / Heating
3: (i) H2, Raney-Ni, (ii) aq. HCl
View Scheme
参考文献
Itier,J.; Casadevall,A.
Bulletin de la Societe Chimique de France, 1969 , p. 2342 - 2355
