顺式-1-(2,6,6-三甲基-2-环己烯-1-基)-2-丁烯-1-酮; 乙位二氢突厥酮合成路线 （共 9 条）
反应条件
potassium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=25°C; Yield given. Yields of byproduct given;
参考文献
Snowden, Roger L.; Linder, Simon M.; Muller, Bernard L.; Schulte, Karl H.
Helvetica Chimica Acta, 1987 , vol. 70, p. 1858 - 1878
反应条件
1: 52 percent / NaOH, H2O2 / methanol; H2O 2: 96 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h / 0 °C 3: 89 percent / CBr4, PPh3 / pyridine / 12 h / 0 °C 4: 80 percent / Zn, CuI / aq. ethanol / sonication 5: 1.) MnO2; 2.) p-TsOH / 1.) pentane, 24 h; 2.) THF, reflux, 4 h View Scheme
参考文献
Sarandeses, Luis A.; Luche, Jean-Louis
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2757 - 2760
反应条件
1: 80 percent / Zn, CuI / aq. ethanol / sonication 2: 1.) MnO2; 2.) p-TsOH / 1.) pentane, 24 h; 2.) THF, reflux, 4 h View Scheme
参考文献
Sarandeses, Luis A.; Luche, Jean-Louis
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2757 - 2760
反应条件
1: 89 percent / CBr4, PPh3 / pyridine / 12 h / 0 °C 2: 80 percent / Zn, CuI / aq. ethanol / sonication 3: 1.) MnO2; 2.) p-TsOH / 1.) pentane, 24 h; 2.) THF, reflux, 4 h View Scheme
参考文献
Sarandeses, Luis A.; Luche, Jean-Louis
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2757 - 2760
反应条件
1: 96 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h / 0 °C 2: 89 percent / CBr4, PPh3 / pyridine / 12 h / 0 °C 3: 80 percent / Zn, CuI / aq. ethanol / sonication 4: 1.) MnO2; 2.) p-TsOH / 1.) pentane, 24 h; 2.) THF, reflux, 4 h View Scheme
参考文献
Sarandeses, Luis A.; Luche, Jean-Louis
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2757 - 2760
反应条件
1: 86 percent / Mg / tetrahydrofuran / Heating 2: KH / hexamethylphosphoric acid triamide / 25 °C View Scheme
参考文献
Snowden, Roger L.; Linder, Simon M.; Muller, Bernard L.; Schulte, Karl H.
Helvetica Chimica Acta, 1987 , vol. 70, p. 1858 - 1878
反应条件
manganese(IV) oxide; toluene-4-sulfonic acid 1.) pentane, 24 h; 2.) THF, reflux, 4 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Sarandeses, Luis A.; Luche, Jean-Louis
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2757 - 2760
反应条件
n-butyllithium; toluene-4-sulfonic acid; diisopropylamine 1.) hexane, THF, 0 deg C, 1 h, 20 deg C, 2 h, 2.) toluene, 20 deg C, 15 h; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Fehr, Charles; Galindo, Jose
Helvetica Chimica Acta, 1986 , vol. 69, p. 228 - 235
反应条件
in pentane Irradiationfurther solvents; Product distributionMechanism;
参考文献
Visser, Cornelis P.; Cerfontain, Hans
Recueil: Journal of the Royal Netherlands Chemical Society, 1983 , vol. 102, # 6 p. 307 - 311
