对甲苯磺酸(S)-(-)-2,2-二甲基-1,3-二氧戊环基-4-基甲基酯合成路线 （共 20 条）
参考文献
Seki; Takezaki; Ohuchi; Saitoh; Ishimori; Yasuda
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 10 p. 1719 - 1723
反应条件
1: LiAlH4 / tetrahydrofuran / 2 h / Heating 2: aq. NaIO4 / tetrahydrofuran / 2 h / 0 °C 3: NaBH4 / ethyl acetate; ethanol / 2.5 h / Ambient temperature 4: 80.3 percent / pyridine / Ambient temperature View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 6, # 5 p. 1181 - 1190
反应条件
pyridine T=4 - 20°C; 28 h;
参考文献
El-Essawy, Farag A.; Khattab, Ahmed F.
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 3 p. 311 - 316
反应条件
1: NaBH4 / ethyl acetate; ethanol / 2.5 h / Ambient temperature 2: 80.3 percent / pyridine / Ambient temperature View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 6, # 5 p. 1181 - 1190
反应条件
trifluorormethanesulfonic acid in acetone 1 h; Ambient temperature;
参考文献
Jindrich, Jindrich; Holy, Antonin; Dvorakova, Hana
Collection of Czechoslovak Chemical Communications, 1993 , vol. 58, # 7 p. 1645 - 1667
反应条件
1: 1.) lead tetraacetate, 2.) sodium borohydride, 3.) sodium hydroxide / 1.) ethyl acetate, 0 deg C, 1 h; 25 deg C, 1 h, 2.) ethanol, 0 deg C, 1 h; 25 deg C, 1 h, 3.) 1 h 2: 91 percent / triethylamine / CHCl3 / 1.) 0 deg C, 30 min, 2.) room temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, # 20 p. 6304 - 6311
反应条件
toluene-4-sulfonic acid in Petroleum ether 4 h; Heating;
参考文献
Bosetti, Aldo; Bianchi, Daniele; Cesti, Pietro; Golini, Paolo; Spezia, Sandro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 18 p. 2395 - 2398
反应条件
1: 71 percent / HCl / dioxane / 12 h 2: 1.) sodium periodate, 2.) NaBH4 / 1.) H2O, dioxane, room temperature, 20 min, 2.) room temperature, 30 min 3: 90 percent / trifluoromethanesulfonic acid / acetone / 1 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 58, # 7 p. 1645 - 1667
反应条件
1: 1.) sodium periodate, 2.) NaBH4 / 1.) H2O, dioxane, room temperature, 20 min, 2.) room temperature, 30 min 2: 90 percent / trifluoromethanesulfonic acid / acetone / 1 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 58, # 7 p. 1645 - 1667
反应条件
1: 45 percent / various solvent(s) / 5 h / 25 °C / lipase PS on Celite 577 2: 82 percent / toluene-p-sulfonic acid (PTSA) / methanol / 3 h / 60 °C 3: 80 percent / toluene-p-sulfonic acid (PTSA) / light petroleum / 4 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 18 p. 2395 - 2398
