4-溴-2,6-二甲基苯酚合成路线 (共 34 条)
反应条件
aluminum tri-bromide; chloroform; bromine T=55°C;
参考文献
Gleed; Peters
Journal of the Chemical Society, 1948 , p. 209,211
反应条件
1: potassium carbonate / acetone / 48 h / 60 °C / Inert atmosphere 2: N-bromosuccinmide; dibenzoyl peroxide / methyl acetate / 48 h / 85 °C View Scheme
参考文献
Sookcharoenpinyo, Bunyarithi; Klein, Emmanuel; Ferrand, Yann; Walker, D. Barney; Brotherhood, Peter R.; Ke, Chenfeng; Crump, Matthew P.; Davis, Anthony P.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 19 p. 4586 - 4590
反应条件
2,3,5-trimethyl-pyridine; copper(l) iodide
Heating;
参考文献
Bacon,R.G.R.; Rennison,S.C.
Journal of the Chemical Society [Section] C: Organic, 1969 , p. 312 - 315
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine in dichloromethane
T=23°C; 1 h;
参考文献
PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2007/1249 A1, 2007 ;
Location in patent: Page/Page column 38-39 ;