3-氨基-5-苯基呋喃-2-甲腈合成路线 （共 2 条）
反应条件
1: formaldehyde cyanohydrin With sodium hydride; magnesium sulfate in tetrahydrofuran 1 h; 2: (Z)-β-bromocinnamonitrile in tetrahydrofuran T=20°C; 1 h; Further stages.;
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
反应条件
1.1: 98 percent / PBr3 / 48 h / 170 °C 2.1: MgSO4; NaH / tetrahydrofuran / 1 h 2.2: 90 percent / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Norman; Chen; Fotsch; Hale; Han; Hurt; Jenkins; Kincaid; Liu; Lu; Moreno; Santora; Sonnenberg; Karbon
Journal of Medicinal Chemistry, 2000 , vol. 43, # 22 p. 4288 - 4312
