5-(4-甲氧基苯基)-1,3,4-恶二唑-2-硫酮合成路线 (共 9 条)
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Journal of the Chinese Chemical Society, , vol. 52, # 3 p. 539 - 544
反应条件
in N,N-dimethyl-formamide 0.00833333 h; Irradiation;
参考文献
Joshi, Sachin; Karnik
Synthetic Communications, 2002 , vol. 32, # 1 p. 111 - 114
反应条件
1: 95 percent / hydrazine hydrate / ethanol 2: 81 percent / dimethylformamide View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 16 p. 4842 - 4850
反应条件
1: thionyl chloride / 13 h / 0 - 50 °C / |Inert atmosphere 2: hydrazine hydrate / ethanol / 48 h / |Reflux 3: triethylamine / ethanol / |Inert atmosphere; |Reflux View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 61, p. 26 - 40
反应条件
in N,N-dimethyl-formamide
参考文献
Macaev, Fliur; Rusu, Ghenadie; Pogrebnoi, Serghei; Gudima, Alexandru; Stingaci, Eugenia; Vlad, Ludmila; Shvets, Nathaly; Kandemirli, Fatma; Dimoglo, Anatholy; Reynolds, Robert
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 16 p. 4842 - 4850
反应条件
1: hydrazine hydrate / methanol / 6 h / Heating 2: KOH / ethanol / 8 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 8 p. 2278 - 2282
反应条件
1: KOH 2: Heating View Scheme
参考文献
Heterocycles, , vol. 20, # 11 p. 2211 - 2224
反应条件
hydrazine hydrate 0.133333 h; microwave irradiation;
参考文献
Joshi; Karnik
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 4 p. 1057 - 1059
反应条件
potassium hydroxide in methanol
Condensation; Heating;
参考文献
Chu, Chang-Hu
Journal of the Chinese Chemical Society, 1999 , vol. 46, # 2 p. 229 - 232