4-羟基-8-三氟甲基喹啉-3-甲酸合成路线 （共 4 条）
反应条件
lithium hydroxide hydrate in methanol T=0°C; 2.16667 h;
参考文献
Garudachari; Isloor, Arun M.; Satyanarayana; Fun, Hoong-Kun; Hegde, Gurumurthy
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 324 - 332
反应条件
1: dowtherm / 5 h / 250 °C 2: lithium hydroxide hydrate / methanol / 2.17 h / 0 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 68, p. 422 - 432
反应条件
1: 6 h / 110 °C 2: dowtherm / 5 h / 250 °C 3: lithium hydroxide hydrate / methanol / 2.17 h / 0 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 68, p. 422 - 432
反应条件
N-bromosuccinmide in tetrahydrofuran
T=20°C; 12 h;
参考文献
Garudachari; Isloor, Arun M.; Satyanarayana; Fun, Hoong-Kun; Hegde, Gurumurthy
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 324 - 332
