1-乙基-4-氧代-1,4-二氢喹啉-3-羧酸合成路线 （共 16 条）
反应条件
sulfuric acid in water; acetic acid 1.5 h; Heating;
参考文献
Grohe, Klaus; Heitzer, Helmut
Liebigs Annalen der Chemie, 1987 , p. 29 - 37
反应条件
1: 81 percent / Ac2O / montmorillonite K-10 / 8 h / 130 - 140 °C 2: 85 percent / acetonitrile / 3 h / Heating 3: NaH / dioxane / 3.5 h / Heating 4: 0.324 g / KOH / methanol; H2O / 3 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 30, # 14 p. 2533 - 2540
反应条件
sodium hydroxide 3 h; Heating;
参考文献
Torii, Sigeni; Okumoto, Hiroshi; Xu, Long He
Tetrahedron, 1991 , vol. 47, # 4-5 p. 665 - 674
反应条件
1: NaH / dioxane / 3.5 h / Heating 2: 0.324 g / KOH / methanol; H2O / 3 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 30, # 14 p. 2533 - 2540
反应条件
1: 97 percent / pyridine, 4-N,N-dimethylaminopyridine / CH2Cl2 / 1.) 0 deg C, 2.) 3 h, room temperature 2: 79.2 percent / NaH / tetrahydrofuran / 10 h / Heating 3: 67 percent / Et4NOTs, HOAc, t-BuOH / Ambient temperature; anodic oxidation (3.3 mA cm-1); var. electrolyte, var. solvent, var. electricity 4: K2CO3 / dimethylformamide / 75 - 80 °C 5: 91.7 percent / 2N aq. NaOH / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 47, # 4-5 p. 665 - 674
反应条件
1: 79.2 percent / NaH / tetrahydrofuran / 10 h / Heating 2: 67 percent / Et4NOTs, HOAc, t-BuOH / Ambient temperature; anodic oxidation (3.3 mA cm-1); var. electrolyte, var. solvent, var. electricity 3: K2CO3 / dimethylformamide / 75 - 80 °C 4: 91.7 percent / 2N aq. NaOH / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 47, # 4-5 p. 665 - 674
反应条件
1: K2CO3 / dimethylformamide / 75 - 80 °C 2: 91.7 percent / 2N aq. NaOH / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 47, # 4-5 p. 665 - 674
反应条件
1: 67 percent / Et4NOTs, HOAc, t-BuOH / Ambient temperature; anodic oxidation (3.3 mA cm-1); var. electrolyte, var. solvent, var. electricity 2: K2CO3 / dimethylformamide / 75 - 80 °C 3: 91.7 percent / 2N aq. NaOH / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 47, # 4-5 p. 665 - 674
反应条件
1: 89.5 percent / Et4NOTs, HOAc, t-BuOH / 1.) anodic oxidation (3.3 mA cm-1), room temperature, 2.) 1 d, room temperature 2: K2CO3 / dimethylformamide / 75 - 80 °C 3: 91.7 percent / 2N aq. NaOH / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 47, # 4-5 p. 665 - 674
反应条件
1: 68.9 percent / NaH / tetrahydrofuran / 3 h / Heating 2: 89.5 percent / Et4NOTs, HOAc, t-BuOH / 1.) anodic oxidation (3.3 mA cm-1), room temperature, 2.) 1 d, room temperature 3: K2CO3 / dimethylformamide / 75 - 80 °C 4: 91.7 percent / 2N aq. NaOH / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 47, # 4-5 p. 665 - 674
