2-甲基-1,3-苯并噻唑3-氧化物合成路线 （共 8 条）
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia 2: acetic acid 3: Et3N / acetone / Heating 4: NaOH / Ambient temperature 5: aq. HCl 6: aq. HCl 7: 2-methyl-propan-2-ol View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
sodium dithionite in ethanol; water T=70 - 80°C; 1.5 h;
参考文献
, vol. 1984, # 6 p. 1100 - 1108
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia 2: acetic acid 3: Et3N / acetone / Heating 4: NaOH / Ambient temperature 5: aq. HCl 6: NH3 / ethanol View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia 2: acetic acid 3: Et3N / acetone / Heating 4: NaOH / Ambient temperature 5: aq. HCl 6: aq. HCl View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia
2: acetic acid
3: Et3N / acetone / Heating
4: NaOH / Ambient temperature
5: aq. HCl
6: aq. HCl
7: CH2Cl2 / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia
2: acetic acid
3: Et3N / acetone / Heating
4: NaOH / Ambient temperature
5: aq. HCl
6: N2H4*H2O / ethanol / Heating
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia
2: acetic acid
3: Et3N / acetone / Heating
4: NaOH / Ambient temperature
5: aq. HCl
6: aq. HCl
7: aq. NaHSO3 / Ambient temperature
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
反应条件
1: NaNH2, isopentyl nitrite / liquid ammonia
2: acetic acid
3: Et3N / acetone / Heating
4: NaOH / Ambient temperature
5: aq. HCl
6: aq. HCl
7: (i) PhLi, Et2O, THF, (ii) /BRN= 1900390/
View Scheme
参考文献
Takahashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, p. 1176 - 1184
