17Alpha-羟基孕烯醇酮-17-乙酸酯合成路线 （共 8 条）
反应条件
sodium tetrahydroborate in ethanol Ambient temperatureother reagent;
参考文献
Joannou; Reeder
Steroids, 1996 , vol. 61, # 1 p. 18 - 21
3517-38-2(17-乙酰基-3-乙酰氧基-10,13-二甲基-1,2,3,4,7,8,9,11,12,14,15,16-十二氢环戊烯并[a]菲-17-基)乙酸酯
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参考文献
Journal of the American Chemical Society, , vol. 78, p. 820,823
参考文献
Journal of the American Chemical Society, , vol. 81, p. 5991
反应条件
1: 92 percent / aq. HClO4 / ethyl acetate / 0.1 h 2: 89 percent / NaBH4 / ethanol / Ambient temperature; other reagent View Scheme
参考文献
Steroids, , vol. 61, # 1 p. 18 - 21
反应条件
sodium hydroxide; water 3 h; Heating;
参考文献
Joannou; Reeder
Steroids, 1996 , vol. 61, # 1 p. 18 - 21
反应条件
MPPA; diethyl ether; chloroform
参考文献
Bowers et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 5991
反应条件
1: chloroform; monoperoxyphthalic acid; diethyl ether 2: ether BF3 3: CrO3; acetone 4: HCl View Scheme
参考文献
Bowers et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 5991
→
3517-38-2(17-乙酰基-3-乙酰氧基-10,13-二甲基-1,2,3,4,7,8,9,11,12,14,15,16-十二氢环戊烯并[a]菲-17-基)乙酸酯
反应条件
toluene-4-sulfonic acid microwave irradiation;
参考文献
Zmijewski, Michal A.; Li, Wei; Zjawiony, Jordan K.; Sweatman, Trevor W.; Chen, Jianjun; Miller, Duane D.; Slominski, Andrzej T.
Steroids, 2009 , vol. 74, # 2 p. 218 - 228
